Treatment of Word Finding Difficulties and Verbal Retrieval Deficits in Civilians Who Sustain a Chronic Traumatic Brain Injury With High Definition Transcranial Direct Current Stimulation
Abstract
The purpose of the study is to test whether low level electric stimulation, called transcranial Direct Current Stimulation (tDCS), on the part of the brain (i.e., pre-supplementary motor area) thought to aid in memory will improve verbal retrieval in civilian (non-military, non-veteran) participants with histories of traumatic brain injuries. The primary outcome measures are neuropsychological assessments of verbal retrieval, and the secondary measures are neuropsychological assessments of other cognitive abilities and electroencephalography (EEG) measures. Additionally, the study will examine the degree to which baseline assessments of cognition, concussion history, structural brain imaging, and EEG predict responses to treatment over time, both on assessments administered within the intervention period and at follow-up.
Conditions: Traumatic Brain Injury, Word Finding Difficulty, Acquired Brain Injury, Cognitive Change.
Primary outcome: The Controlled Oral Word Association Test; Category Fluency; The Boston Naming Test; Semantic Object Retrieval Test; The Delis Kaplan Color Word Interference Test, Naming; The Delis Kaplan Color Word Interference Test, Reading; The Delis Kaplan Color Word Interference Test, Inhibition; The Delis Kaplan Color Word Interference Test, Inhibition and Switching; Rey Auditory Verbal Learning Test and Alternative Lists, Total Learning; Rey Auditory Verbal Learning Test and Alternative Lists, Delayed Recall.
Enrollment: 5 participants.
How strong is the evidence?
Evidence Hub reads this as a clinical trial, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence. Reported size: 5 participants or records.
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