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METAL: fast and efficient meta-analysis of genomewide association scans

C. Willer, Yun Li, G. Abecasis

Bioinform., 2010

5,206 citations

Abstract

Summary: METAL provides a computationally efficient tool for meta-analysis of genome-wide association scans, which is a commonly used approach for improving power complex traits gene mapping studies. METAL provides a rich scripting interface and implements efficient memory management to allow analyses of very large data sets and to support a variety of input file formats. Availability and implementation: METAL, including source code, documentation, examples, and executables, is available at http://www.sph.umich.edu/csg/abecasis/metal/ Contact: [email protected]

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