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Human pain neuroscience and the next generation of pain therapeutics

Copits BA, Curatolo M, Dougherty PM, Gereau RW, Luo W, Martone M, Olausson H, Price TJ et al.

Neuron, 2025

10 citations

Abstract

The recent approval of suzetrigine for acute pain treatment highlights both the success of targeting peripheral sensory neurons for pain management and the potential of developing new pain therapies primarily in human-based systems. To realize this transformative potential, further research into somatosensation and pain neuroimmunology in human systems is essential.

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