Frequency of prediabetes in women with polycystic ovary syndrome
Abstract
INTRODUCTION: In approximately 50-70% of all women with PCOS (Polycystic Ovarian Syndrome) may be found lower or higher degree insulin resistance, while insensitivity to insulin cells very likely contributes hyperandrogenaemia which is responsible for the symptoms and signs of PCOS. Insulin resistance, PCOS and prediabetes are linked.
MATERIAL AND METHODS: This research is retrospective-prospective, clinical, comparative and descriptive. The study included 60 women with PCOS, aged 20-40 years, with no acute or chronic diseases, divided into two groups: PCOS women with elevated body weight and PCOS women with normal body weight. The control group is consisted of 30 female subjects without PCOS, aged 20-40 years. The research is conducted at the Clinic for Endocrinology and Diabetes and the department of diagnostic and outpatient clinics at CCU Sarajevo and in BKH Niedernbayern. In all subjects the following will be performed: clinical evaluation, laboratory tests and ovarian echosonography.
RESULTS AND DISCUSSION: Subjects with PCOS had significantly higher values of body weight, BMI and waist circumference in relation to a group of healthy subjects. Disturbance of the menstrual cycle was present in 57% of women with PCOS. Disturbance of the menstrual cycle was more common in PCOS patients with elevated body weight in relation to PCOS patients with normal body weight. Progesterone values showed that in the PCOS group, 85% of anovulatory cycle in contrast to the control group,…
How strong is the evidence?
Evidence Hub reads this as a case-control, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause. Reported size: 60 participants or records.
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