Controlled natural cycle IVF: a novel approach for a dominant follicle during an in-vitro maturation cycle
Abstract
The objective of this retrospective analysis is to evaluate whether patients developing a dominant follicle in an in-vitro maturation (IVM) programme can be included in a natural cycle IVF (nIVF) programme. In a university teaching hospital, a total of 38 patients with polycystic ovarian syndrome were treated by metformin before undergoing an IVM cycle. Controlled nIVF was performed on seven patients with a dominant follicle. This paper reports three ongoing pregnancies from five embryo transfers in the latter group. Hence, nIVF can be a novel approach for women developing a dominant follicle during an IVM cycle.
How strong is the evidence?
Evidence Hub reads this as a cohort study, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence. Reported size: 38 participants or records.
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