Suzetrigine for pain relief: Key considerations for nurses
Abstract
Abstract: Suzetrigine (JOURNAVX) is a novel oral medication approved in January 2025 for the treatment of moderate-to-severe acute pain in adults. It works by selectively inhibiting NaV1.8 voltage-gated sodium channels, which play a key role in pain transmission through peripheral sensory neurons. This targeted mechanism offers potential advantages over current pain management options. Clinical trials have demonstrated efficacy in reducing pain intensity following surgical procedures, making it a promising alternative to opioids. For nurses, suzetrigine represents an important addition to multimodal pain management strategies. Nurses play a key role in educating patients about its use, monitoring for adverse effects, and ensuring adherence to proper dosing guidelines. As suzetrigine becomes more widely available, health care professionals need to understand its benefits, risks, and proper use. This article provides an overview of its mechanism of action, adverse effects, dosing guidelines, cost considerations, and potential role in pain management.
Read the paper
Related studies
- Noninvasive and Point-of-Care Surface-Enhanced Raman Scattering (SERS)-Based Breathalyzer for Mass Screening of Coronavirus Disease 2019 (COVID-19) under 5 min
- De Novo Transcriptome Analysis and Detection of Antimicrobial Peptides of the American Cockroach Periplaneta americana (Linnaeus)
- Molecular Characterization and Expression Profiling of Tomato GRF Transcription Factor Family Genes in Response to Abiotic Stresses and Phytohormones
- Assembly of Tight Junction Strands: Claudin-10b and Claudin-3 Form Homo Tetrameric Building Blocks that Polymerise in a Channel-Independent Manner
- Update of the Pompe variant database for the prediction of clinical phenotypes: Novel disease‐associated variants, common sequence variants, and results from newborn screening
- Machine Learning-Based SERS Chemical Space for Two-Way Prediction of Structures and Spectra of Untrained Molecules
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.