Metformin hydrochloride and recurrent miscarriage in a woman with polycystic ovary syndrome
Abstract
OBJECTIVE: To report the effect of metformin treatment on a patient with recurrent miscarriage (RM) and polycystic ovary syndrome (PCOS).
DESIGN: Case report.
SETTING: University department of obstetrics and gynecology, Italy.
PATIENT(S): A woman complaining of RM who had PCOS and insulin resistance.
INTERVENTION(S): Clinical, biochemical, and instrumental assessments.
MAIN OUTCOME MEASURE(S): Administration of metformin hydrochloride before and throughout pregnancy.
RESULT(S): After 3 months of treatment, the patient became pregnant. The pregnancy had a physiologic development, and at 39 weeks of gestation, the patient spontaneously delivered a healthy infant.
CONCLUSION(S): Metformin has shown to be effective in an insulin-resistant PCOS woman with RM.
How strong is the evidence?
Evidence Hub reads this as a case report, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.
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