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Probable Cinnamon-Induced Mixed Hepatocellular-Cholestatic Liver Injury in a Young Woman: A Case Report

Yesukumar SJ, Bakir L, Mohamed IA, Danjuma M

Cureus, 2025

Abstract

Reliable data on the safety of herbal medicines remains suboptimal. The consumption of these products is not without unanticipated harmful effects. Cinnamon, an herbal extract containing alkaloids such as coumarin, has been implicated in herb-induced liver injury (HILI). This report describes a rare case of HILI in a 34-year-old female, attributed to prolonged ingestion of cinnamon for weight loss purposes. She presented with abdominal pain, jaundice, and dark urine. Laboratory studies were consistent with acute liver injury. Cinnamon was immediately discontinued, and the patient was treated conservatively. On following visits, her liver biochemistry was back to normal with complete resolution of earlier features of hepatocellular injury.

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