Case report: A successful live birth after in vitro fertilization and embryo transfer in a patient with endometrial cancer who was treated conservatively
Abstract
Objective: To describe a patient conceiving with in vitro fertilization and embryo transfer(IVF-ET) after conservative treatment of early stage endometrial cancer.
Patient: A 31-year-old multiparous woman diagnosed with highly-differentiated (G1) endometrial adenocarcinoma (grade IA).
Interventions: After four courses of conservative treatment each followed by hysteroscopic biopsy and endometrial curettage,assisted reproductive technology was performed.
Main outcome measures: Successful pregnancy and delivery without residual endometrial cancer.
Resultss: A healthy normal female infant with a birth weight of 3,690 g was born by cesarean section at 38 + 2 weeks' gestation. No residual malignant cells was detected on a biopsy during cesarean section.
Conclusions: Conservative fertility-sparing treatment are crucial for young patients with early stage endometrial cancer. Assisted reproductive technologies may be considered to assist such patients to conceive as soon as possible.
How strong is the evidence?
Evidence Hub reads this as a case report, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.
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