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Brucellar spondylitis occurring in the cervical vertebra: a rare case report and literature review

Zhang J, Li J, Chen J, Hao Y, Liu Y, Xie S, Wen H

Frontiers in medicine, 2026

Abstract

Introduction: Brucellosis is a zoonotic disease, which can cause systemic infections involving multiple organs. In musculoskeletal diseases, spondylitis is the most common complication of brucellosis, mainly affecting the lumbar and thoracic vertebrae, and rarely involving the cervical vertebrae. Brucellosis-induced cervical spondyloarthritis represents a severe and rare clinical manifestation of brucellosis, potentially leading to permanent damage and neurological dysfunction.

Case presentation: This case report involves a 66-years-old male with a rare case of cervical spondylitis caused by Brucella. The diagnosis was based on the patient's epidemiological history, laboratory tests, and imaging examinations. After triple therapy with doxycycline, rifampicin, and ceftriaxone for the treatment of brucellosis, the patient's symptoms improved.

Conclusion: Early diagnosis and treatment of spondylitis caused by Brucella are very important for the prognosis of patients.

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Evidence Hub reads this as a case report, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.

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