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Suzetrigine (Journavx) - a sodium channel blocker for acute pain

The Medical letter on drugs and therapeutics, 2025

10 citations

Abstract

The FDA has approved suzetrigine (Journavx – Vertex), a selective sodium channel blocker, for oral treatment of moderate to severe acute pain in adults. Suzetrigine is the first sodium channel blocker to be approved in the US for this indication and the first oral nonopioid drug to be approved for treatment of pain in over 25 years.

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