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FDA approves Journavx (Suzetrigine) as the first non-opioid treatment for moderate to severe acute pain

M. Aamir, Pinkey Kumari, Muhammad Taha Altaf, Mohammed Quader Naseer, M. O. Oduoye, Moses Adewole

Annals of Medicine and Surgery, 2025

1 citation

Abstract

Acute pain is a sudden-onset condition that typically lasts less than 6 months and can significantly affect daily life, well-being, and healthcare costs. Management options include nonsteroidal anti-inflammatory drugs such as aspirin and ibuprofen, aceta-minophen, corticosteroids, and opioids. In severe cases, opioids may be necessary, but their use is limited by side effects, such as hypoventilation, nausea, vomiting, constipation, CNS depression, and renal dysfunction [1] . Opioids continue to play a key role in pain management, but their use must minimize risks while maximizing benefits.

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