Browse studies, page 214
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- Sildenafil citrate to improve colour doppler indices in patient with pre-eclampsia: a path less taken 2020
- Aqueous Extract of Perilla frutescens var. acuta Relaxes the Ciliary Smooth Muscle by Increasing NO/cGMP Content In Vitro and In Vivo Molecules, 2018
- Factors determining the oral absorption and systemic disposition of zeaxanthin in rats: in vitro, in situ, and in vivo evaluations Pharmaceutical Biology, 2022
- Immunosuppression by hydroxychloroquine: mechanistic proof in in vitro experiments but limited systemic activity in a randomized placebo-controlled clinical pharmacology study Immunologic research, 2023
- Modulation of penile erection in rabbits by Mondia whitei: possible mechanism of action African Journal of Traditional Complementary and Alternative Medicines, 2010
- Aphrodisiac Potentials of Pausinystalia yohimbe (K. Schum.) Pierre ex Beille Methanol Root Extract in Male Wistar Rats 2020
- PDE-5 inhibitors in selected herbal supplements from the Ghanaian market for better erectile function as tested by a bioassay Toxicology in Vitro, 2021
- Are Adverse Effects of Sildenafil also Caused by Inhibition of Diamine Oxidase? Urologia internationalis, 2001
- Aphrodisiac Potential of Hibiscus sabdariffa: Phosphodiesterse-5 Inhibition and Sexual Behavior Study Using in Silico and in Vivo Models Natural Resources for Human Health, 2026
- A statistical approach to development of taste masked effervescent tablets of sildenafil citrate containing kyron T134 2020
- Comparative Assessment of Critical Quality Attributes of Sildenafil Tablets Dissolution Technologies, 2021
- In vitro and in vivo effects of Khaya grandifoliola C. DC. (Meliaceae) leaf on erectile dysfunction in male rats Nigerian Journal of Pharmaceutical Research, 2022
- Formulation and evaluation of taste-masked oral disintegrating tablet containing tolterodine-loaded montmorillonite Research in pharmaceutical sciences, 2023
- Development and Optimisation of Inhalable EGCG Nano-Liposomes as a Potential Treatment for Pulmonary Arterial Hypertension by Implementation of the Design of Experiments Approach Pharmaceutics, 2023
- Deciphering the myth of icariin and synthetic derivatives in improving erectile function from a molecular biology perspective: a narrative review Translational andrology and urology, 2022
- Quality by Design and In Silico Approach in SNEDDS Development: A Comprehensive Formulation Framework Pharmaceutics, 2025
- Case report and literature review: Giant retroperitoneal cystic lymphangioma Frontiers in surgery, 2023
- Preparation of oyster peptide and Pfaffia glomerata pressed candy and its ameliorative effect on sexual dysfunction in male mice Food science & nutrition, 2024
- Isolation, bioassay and 3D-QSAR analysis of 8-isopentenyl flavonoids from Epimedium sagittatum maxim. as PDE5A inhibitors Chinese medicine, 2022
- Chemsex and Psychosis: A Systematic Review Behavioral sciences (Basel, Switzerland), 2022
- Ameliorative Sexual Behavior and Phosphodiesterase-5 Inhibitory Effects of Spondias mangifera Fruit Extract in Rodents: In Silico, In Vitro, and In Vivo Study Journal of clinical medicine, 2022
- Comparison of the Surgical Outcomes in Neonates with Left-sided Congenital Diaphragmatic Hernia with Only Skin Closure versus Abdominal Muscle Closure Journal of Indian Association of Pediatric Surgeons, 2024
- Hydrogel technologies in andrology: advances in research and prospective applications Frontiers in pharmacology, 2025
- Severe bronchospasm and acute respiratory failure associated with inhaled prostacyclin therapy Pulmonary circulation, 2024
- The Quest for Child-Friendly Carrier Materials Used in the 3D Semi-Solid Extrusion Printing of Medicines Pharmaceutics, 2022
- Development and Optimization of Sildenafil Orodispersible Mini-Tablets (ODMTs) for Treatment of Pediatric Pulmonary Hypertension Using Response Surface Methodology Pharmaceutics, 2023
- Polyelectrolyte-based solid dispersions for enhanced dissolution and pH-Independent controlled release of sildenafil citrate Heliyon, 2023
- The Physicochemical Compatibility of Sildenafil Injection with Parenteral Medications Used in Neonatal Intensive Care Settings Pharmaceutics, 2024
- Psilocin, A Psychedelic Drug, Exerts Anticonvulsant Effects Against PTZ- and MES-Induced Seizures in Mice via 5-HT1A and CB1 Receptors: Involvement of Nitrergic, Opioidergic, and Kynurenine Pathways Pharmacology research & perspectives, 2025
- Comprehensive chemical analysis of polyphenols in the ethyl acetate extract from the roots of Ephedra sinica Stapf and evaluation of its therapeutic effects on SU5416/hypoxia-induced pulmonary arterial hypertension rats Bioresources and bioprocessing, 2025
- Colon-targeted pH-responsive tofacitinib beads improve ulcerative colitis outcomes with lower systemic exposure Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society, 2026
- \Stopping Dysmenorrhea: A Systematic Review of Drugs Inhibiting Uterine Contractions Journal of endometriosis and uterine disorders, 2026
- Sildenafil citrate inhibits agonist induced contractions in isolated rat seminal vesicles The Journal of urology, 2006
- Chemotherapeutic efficacy of phosphodiesterase inhibitors in chagasic cardiomyopathy JACC. Basic to translational science, 2016
- Effects of sildenafil (viagra) on human myocardial contractility, in vitro arrhythmias, and tension of internal mammaria arteries and saphenous veins Journal of cardiovascular pharmacology, 2003
- Ex-vivo antioxidant, enzyme inhibitory properties and computational analysis unveil the molecular mechanism of cardiac and penile phosphodiesterase-5 inhibition by bacterial strain HOKA1 extract as an aphrodisiac's agent International journal of biological macromolecules, 2024
- Expression of cyclic AMP-dependent protein kinase isoforms in human cavernous arteries: functional significance and relation to phosphodiesterase type 4 The journal of sexual medicine, 2010
- Effects of two selective phosphodiesterase type 5 inhibitors, sildenafil and vardenafil, on object recognition memory and hippocampal cyclic GMP levels in the rat Neuroscience, 2002
- Astragaloside IV ameliorates pulmonary vascular remodeling in hypoxia-induced pulmonary hypertension by restraining the T follicular helper cell response and expanding T follicular regulatory cell response Phytomedicine : international journal of phytotherapy and phytopharmacology, 2022
- In vitro and in vivo aphrodisiac properties of the seed extract from Allium tuberosum on corpus cavernosum smooth muscle relaxation and sexual behavior parameters in male Wistar rats BMC complementary and alternative medicine, 2017
- Inhibition of cyclic GMP hydrolysis in human corpus cavernosum smooth muscle cells by vardenafil, a novel, selective phosphodiesterase type 5 inhibitor Life sciences, 2001
- Effect of the selective phosphodiesterase type 5 inhibitor sildenafil on erectile dysfunction in the anesthetized dog The Journal of urology, 1998
- BAY 41-2272, a soluble guanylate cyclase stimulator, relaxes isolated human ureter in a standardized in vitro model Urology, 2014
- Nitric oxide release from human corpus cavernosum induced by a purified scorpion toxin Urology, 2004
- A comparative study of ethanolic extracts of Pedalium murex Linn. fruits and sildenafil citrate on sexual behaviors and serum testosterone level in male rats during and after treatment Journal of ethnopharmacology, 2012
- Sildenafil effect on the human bladder involves the L-cysteine/hydrogen sulfide pathway: a novel mechanism of action of phosphodiesterase type 5 inhibitors European urology, 2012
- KMUP-1 relaxes rabbit corpus cavernosum smooth muscle in vitro and in vivo: involvement of cyclic GMP and K(+) channels British journal of pharmacology, 2002
- In vitro and in vivo aphrodisiac properties of Corchorus depressus Linn. on rabbit corpus cavernosum smooth muscle relaxation and sexual behavior of normal male rats Journal of ethnopharmacology, 2013
- Homocysteine and copper interact to promote type 5 phosphodiesterase expression in rabbit cavernosal smooth muscle cells Asian journal of andrology, 2008
- Nexavar/Stivarga and viagra interact to kill tumor cells Journal of cellular physiology, 2015
- Effects of nitric oxide on the Ca2+-activated potassium channels in smooth muscle cells of the human corpus cavernosum Urological research, 2001
- Evaluation of some prostaglandins modulators on rat corpus cavernosum in-vitro: Is relaxation negatively affected by COX-inhibitors? Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019
- Pro-erectile effect of vardenafil: in vitro experiments in rabbits and in vivo comparison with sildenafil in rats European urology, 2003
- Pharmacokinetics of DA-8159, a new erectogenic, after intravenous and oral administration to rats: hepatic and intestinal first-pass effects Journal of pharmaceutical sciences, 2003
- Absence of clinically important HERG channel blockade by three compounds that inhibit phosphodiesterase 5--sildenafil, tadalafil, and vardenafil European journal of pharmacology, 2004
- Development of a Sildenafil Citrate Microemulsion-Loaded Hydrogel as a Potential System for Drug Delivery to the Penis and Its Cellular Metabolic Mechanism Pharmaceutics, 2020
- Effect of the phosphodiesterase 5 inhibitors sildenafil, tadalafil and vardenafil on rat anococcygeus muscle: functional and biochemical aspects Clinical and experimental pharmacology & physiology, 2009
- Effects of phosphodiesterase inhibitors on the inflammatory response of endothelial cells stimulated by myeloperoxidase-modified low-density lipoprotein or tumor necrosis factor alpha European urology, 2010
- Exploring dual inhibitors Carbonic Anhydrases and Phosphodiesterase 5 as potential agents for treatment Alzheimer's disease European journal of medicinal chemistry, 2026
- Effect of sildenafil on reperfusion function, infarct size, and cyclic nucleotide levels in the isolated rat heart model Cardiovascular drugs and therapy, 2005
- Zinc induces a bell-shaped proliferative dose-response effect in cultured smooth muscle cells from benign prostatic hyperplasia Urology, 2015
- The disposition of three phosphodiesterase type 5 inhibitors, vardenafil, sildenafil, and udenafil, is differently influenced by the CYP3A5 genotype Pharmacogenetics and genomics, 2011
- The impact of polymers on 3D microstructure and controlled release of sildenafil citrate from hydrophilic matrices European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2018
- Inhibition of cGMP phosphodiesterase 5 suppresses matrix metalloproteinase-2 production in pulmonary artery smooth muscles cells Clinical and experimental pharmacology & physiology, 2010
- Discovery of Novel Agents on Spindle Assembly Checkpoint to Sensitize Vinorelbine-Induced Mitotic Cell Death Against Human Non-Small Cell Lung Cancers International journal of molecular sciences, 2020
- Preparation, characterization and in vitro evaluation of a polyvinyl alcohol/sodium alginate based orodispersible film containing sildenafil citrate Die Pharmazie, 2014
- Brief hyperoxia increases mitochondrial oxidation and increases phosphodiesterase 5 activity in fetal pulmonary artery smooth muscle cells Antioxidants & redox signaling, 2012
- Biphasic Effect of Sildenafil on Energy Sensing is Mediated by Phosphodiesterases 2 and 3 in Adipocytes and Hepatocytes International journal of molecular sciences, 2019
- An in vitro and in vivo comparative study of directly compressed solid dispersions and freeze dried sildenafil citrate sublingual tablets for management of pulmonary arterial hypertension Acta pharmaceutica (Zagreb, Croatia), 2012
- Antimitogenic actions of organic nitrates are potentiated by sildenafil and mediated via activation of protein kinase A. Molecular pharmacology, 2001
- Evidence of synergistic/additive effects of sildenafil and erythropoietin in enhancing survival and migration of hypoxic endothelial cells American journal of physiology. Lung cellular and molecular physiology, 2013
- Sublingual Administration of Sildenafil Oro-dispersible Film: New Profiles of Drug Tolerability and Pharmacokinetics for PDE5 Inhibitors Frontiers in pharmacology, 2018
- In vivo dilation of fetal and neonatal ductus arteriosus by inhibition of phosphodiesterase-5 in rats Pediatric research, 2005
- Vardenafil, but not sildenafil or tadalafil, has calcium-channel blocking activity in rabbit isolated pulmonary artery and human washed platelets British journal of pharmacology, 2008
- Hypotensive interaction of sildenafil and nicorandil in rats through the cGMP pathway but not by K(ATP) channel activation Japanese journal of pharmacology, 2000
- Differential effects of the phosphodiesterase type 5 inhibitors sildenafil, vardenafil, and tadalafil in rat aorta The Journal of pharmacology and experimental therapeutics, 2006
- In vitro effects of a novel class of nitric oxide (NO) donating compounds on isolated human erectile tissue European urology, 2002
- Celecoxib dilates guinea-pig coronaries and rat aortic rings and amplifies NO/cGMP signaling by PDE5 inhibition Cardiovascular research, 2007
- Molecular mechanisms underlying rat mesenteric artery vasorelaxation induced by the nitric oxide-independent soluble guanylyl cyclase stimulators BAY 41-2272 [5-cyclopropyl-2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-4-ylamine] and YC-1 [3-(5'-hydroxymethyl-2'-furyl)-1-benzyl Indazole]. The Journal of pharmacology and experimental therapeutics, 2006
- Pharmacological characterization of a novel phosphodiesterase type 5 (PDE5) inhibitor lodenafil carbonate on human and rabbit corpus cavernosum European journal of pharmacology, 2008
- Vasodilatory activity and antihypertensive profile mediated by inhibition of phosphodiesterase type 1 induced by a novel sulfonamide compound Fundamental & clinical pharmacology, 2012
- In vivo and in vitro investigation of the effects of sildenafil on rat cavernous smooth muscle The Journal of urology, 2001
- The augmentation of BK channel activity by nitric oxide signaling in rat cerebral arteries involves co-localized regulatory elements Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2017
- Reduced NO-cGMP signaling contributes to vascular inflammation and insulin resistance induced by high-fat feeding Arteriosclerosis, thrombosis, and vascular biology, 2010
- Spilanthes acmella ethanolic flower extract: LC-MS alkylamide profiling and its effects on sexual behavior in male rats Phytomedicine : international journal of phytotherapy and phytopharmacology, 2011
- Maerua angolensis DC. (Capparaceae) Stem Bark Extract Protects against Pentylenetetrazole-Induced Oxidative Stress and Seizures in Rats Evidence-based complementary and alternative medicine : eCAM, 2018
- Effects of NCX 4050, a new NO donor, in rabbit and human corpus cavernosum International journal of andrology, 2003
- Sildenafil Reduces Expression and Release of IL-6 and IL-8 Induced by Reactive Oxygen Species in Systemic Sclerosis Fibroblasts International journal of molecular sciences, 2020
- Role of K+ and Ca2+ fluxes in the cerebroarterial vasoactive effects of sildenafil European journal of pharmacology, 2008
- Relaxing effects induced by the soluble guanylyl cyclase stimulator BAY 41-2272 in human and rabbit corpus cavernosum European journal of pharmacology, 2003
- Fabrication, appraisal, and transdermal permeation of sildenafil citrate-loaded nanostructured lipid carriers versus solid lipid nanoparticles International journal of nanomedicine, 2011
- Sildenafil (Viagra) prolongs cardiac repolarization by blocking the rapid component of the delayed rectifier potassium current Circulation, 2000
- Role of cGMP in sildenafil-induced activation of endothelial Ca2+-activated K+ channels Journal of cardiovascular pharmacology, 2006
- Functional G-protein-coupled receptor 35 is expressed by neurons in the CA1 field of the hippocampus Biochemical pharmacology, 2015
- Nebulized solid lipid nanoparticles for the potential treatment of pulmonary hypertension via targeted delivery of phosphodiesterase-5-inhibitor International journal of pharmaceutics, 2017
- Characterization of efflux transport of the PDE5 inhibitors, vardenafil and sildenafil The Journal of pharmacy and pharmacology, 2012
- The hypertensive effect of sorafenib is abolished by sildenafil Cardio-Oncology, 2020
- Sildenafil Enhances Neurogenesis and Oligodendrogenesis in Ischemic Brain of Middle-Aged Mouse PLoS ONE, 2012
- Sildenafil reverses cardiac dysfunction in the mdx mouse model of Duchenne muscular dystrophy Carolina Digital Repository (University of North Carolina at Chapel Hill), 2020
- Sildenafil Ameliorates Gentamicin-Induced Nephrotoxicity in Rats: Role of iNOS and eNOS Journal of Toxicology, 2014
