Browse studies, page 267

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• Flaxseed Supplementation Confers Resilience to Stress-Induced Depression-Like Behaviors via GDNF Epigenetic Modulation in the Ventral Tegmental Area of Rats Neuropsychiatric disease and treatment, 2026
• Clinical outcomes of mitochondrial-enhancing nutraceutical supplementation in psychiatric disorders: A systematic review General psychiatry, 2026
• Oxidative stress predicts depressive symptom changes with omega-3 fatty acid treatment in coronary artery disease patients Brain, behavior, and immunity, 2017
• Effect of prenatal EPA and DHA on maternal and umbilical cord blood cytokines BMC pregnancy and childbirth, 2018
• Omega-3 polyunsaturated fatty acid (PUFA) status in major depressive disorder with comorbid anxiety disorders The Journal of clinical psychiatry, 2013
• Omega-3 Fatty Acids: Key Players in Cognitive Function and Brain Health Journal of Education, Health and Sport, 2025
• Role of Omega-3 fatty acids eicosapentaenoic (EPA) and docosahexaenoic (DHA) as modulatory and anti-inflammatory agents in noncommunicable diet-related diseases - Reports from the last 10 years Clinical Nutrition ESPEN, 2024
• Omega-3 Fatty Acids and Mood Disorders: A Critical Narrative Review Lipidology, 2026
• The role of omega-3 fatty acids in sleep deprivation and mental healt: a narrative review International Journal of Innovative Technologies in Social Science, 2026
• Inflammation and treatment response to sertraline in patients with coronary heart disease and comorbid major depression Journal of Psychosomatic Research, 2011
• Integrating Nutrition and Mental Health: Mechanistic Pathways, Clinical Evidence, and Public Health Policy Implications Wah Academia Journal of Health and Nutrition, 2025
• Omega-3 eicosapentaenoic acid in bipolar depression: report of a small open-label study Journal of Clinical Psychiatry, 2005
• Omega-3 as an adjunctive therapy of sertraline and venlafaxine substantially improves symptoms of major depressive disorder: A double-blind, placebo-controlled study Current Psychopharmacology, 2021
• Relationship Between Polyunsaturated Fatty Acids and Psychopathology in the NEURAPRO Clinical Trial Frontiers in Psychiatry, 2019
• RCT: Omega‐3 fatty acids not supported as adjunct therapy for pediatric depression The Brown University Child & Adolescent Psychopharmacology Update, 2026
• The impact of DocosaHexaenoic Acid supplementation during pregnancy and lactation on Neurodevelopment of the offspring in India (DHANI): trial protocol BMC pediatrics, 2018
• Multimodal prehabilitation for major surgery in elderly patients to lower complications: protocol of a randomised, prospective, multicentre, multidisciplinary trial (PREHABIL Trial) BMJ open, 2023
• Effects of cocoa extract and a multivitamin on cognitive function: A randomized clinical trial Alzheimer's & dementia : the journal of the Alzheimer's Association, 2023
• Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) study: Rationale, design and baseline characteristics of a randomized control trial of the MIND diet on cognitive decline Contemporary clinical trials, 2021
• Can broad-spectrum multinutrients treat symptoms of antenatal depression and anxiety and improve infant development? Study protocol of a double blind, randomized, controlled trial (the 'NUTRIMUM' trial) BMC pregnancy and childbirth, 2020
• Development and Validation of a Mobile Application as an Adjuvant Treatment for People Diagnosed with Long COVID-19: Protocol for a Co-Creation Study of a Health Asset and an Analysis of Its Effectiveness and Cost-Effectiveness International journal of environmental research and public health, 2022
• Effects of concentrated long-chain omega-3 polyunsaturated fatty acid supplementation before radical prostatectomy on prostate cancer proliferation, inflammation, and quality of life: study protocol for a phase IIb, randomized, double-blind, placebo-controlled trial BMC cancer, 2018
• Efficacy of Hwangryunhaedok-tang (Huang-lian-jie-du-tang, Oren-gedoku-to) for patients with hyperlipidemia: a study protocol for a randomized, double-blind, placebo-controlled, parallel, investigator-initiated clinical trial Trials, 2020
• A first-in-human phase 1 study of cavrotolimod, a TLR9 agonist spherical nucleic acid, in healthy participants: Evidence of immune activation Frontiers in immunology, 2022
• Prevalence of Physical Activity and Sedentary Behavior Patterns in Generally Healthy European Adults Aged 70 Years and Older-Baseline Results From the DO-HEALTH Clinical Trial Frontiers in public health, 2022
• Randomized Trial of Marine n-3 Polyunsaturated Fatty Acids for the Prevention of Cerebral Small Vessel Disease and Inflammation in Aging (PUFA Trial): Rationale, Design and Baseline Results Nutrients, 2019
• Observed Improvement in Cognition During a Personalized Lifestyle Intervention in People with Cognitive Decline Journal of Alzheimer's disease : JAD, 2023
• There is No Association Between the Omega-3 Index and Depressive Symptoms in Patients With Heart Disease Who Are Low Fish Consumers Heart, lung & circulation, 2017
• The VITamin D and OmegA-3 TriaL-Depression Endpoint Prevention (VITAL-DEP): Rationale and design of a large-scale ancillary study evaluating vitamin D and marine omega-3 fatty acid supplements for prevention of late-life depression Contemporary clinical trials, 2018
• Pain neuroscience education, blended exercises and booster sessions as an effective therapy for pain, functional and psychological factors in patients with knee osteoarthritis: a study protocol for a single-blind randomised controlled trial with 22 factorial design during 6-month follow-up BMJ open, 2023
• Double-blind RCT of fish oil supplementation in pregnancy and lactation to improve the metabolic health in children of mothers with overweight or obesity during pregnancy: study protocol BMJ open, 2020
• Acupoint Thread Embedding Combined With Wenshen Bugu Decoction for the Treatment of Aromatase Inhibitor-Associated Musculoskeletal Symptom Among Postmenopausal Breast Cancer Patients: Study Protocol of a Randomized Controlled Trial Integrative cancer therapies, 2023
• Computerised cognitive training tools and online nutritional group counselling for people with mild cognitive impairment: study protocol of a completely digital, randomised, controlled trial BMJ open, 2022
• Multifaceted intervention to enhance cognition in older people at risk of cognitive decline: study protocol for the Protein Omega-3 and Vitamin D Exercise Research (PONDER) study BMJ open, 2019
• Anamorelin Efficacy in Non-Small-Cell Lung Cancer Patients With Cachexia: Insights From ROMANA 1 and ROMANA 2 Journal of cachexia, sarcopenia and muscle, 2025
• The intake assessment of diverse dietary patterns on childhood hypertension: alleviating the blood pressure and lipidemic factors with low-sodium seafood rich in omega-3 fatty acids Lipids in health and disease, 2020
• Exercise, Mediterranean Diet Adherence or Both during Pregnancy to Prevent Postpartum Depression-GESTAFIT Trial Secondary Analyses International journal of environmental research and public health, 2022
• Effects of Eurycoma longifolia Jack standardised water extract (Physta) on well-being of perimenopausal and postmenopausal women: protocol for a randomised, double-blinded, placebo-controlled, parallel group study BMJ open, 2023
• Pilot Study of Second-Generation DNA Methylation Epigenetic Markers in Relation to Cognitive and Neuropsychiatric Symptoms in Older Adults Journal of Alzheimer's disease : JAD, 2023
• A Sequential Adaptive Intervention Strategy Targeting Remission and Functional Recovery in Young People at Ultrahigh Risk of Psychosis: The Staged Treatment in Early Psychosis (STEP) Sequential Multiple Assignment Randomized Trial JAMA psychiatry, 2023
• Investigating N-3 Fatty Acids to prevent Neonatal Tobacco-related outcomeS (INFANTS): study protocol for a double-blind, randomized, placebo-controlled parallel clinical trial of n-3 polyunsaturated fatty acids in pregnant smokers Trials, 2021
• Multimodal Preventive Trial for Alzheimer's Disease: MIND-ADmini Pilot Trial Study Design and Progress The journal of prevention of Alzheimer's disease, 2022
• Nutritional counselling in adults promoting adherence to the Mediterranean diet as adjuvant in the treatment of major depressive disorder (INDEPT): a randomized open controlled trial study protocol BMC psychiatry, 2023
• Long-Term Adherence to a Mediterranean Diet 1-Year after Completion of the MedLey Study Nutrients, 2022
• A randomized, double-blind, placebo-controlled, hybrid parallel-arm study of low-dose naltrexone as an adjunctive anti-inflammatory treatment for major depressive disorder Trials, 2022
• Low omega-3 index and polyunsaturated fatty acid status in patients with chronic fatigue syndrome/myalgic encephalomyelitis Prostaglandins, leukotrienes, and essential fatty acids, 2018
• Maternal Factors Associated with Levels of Fatty Acids, Specifically n-3 PUFA during Pregnancy: ECLIPSES Study Nutrients, 2021
• The Feasibility of the "Omega Kid" Study Protocol: A Double-Blind, Randomised, Placebo-Controlled Trial Investigating the Effect of Omega-3 Supplementation on Self-Regulation in Preschool-Aged Children Nutrients, 2021
• Potential efficacy of caffeine ingestion on balance and mobility in patients with multiple sclerosis: Preliminary evidence from a single-arm pilot clinical trial PloS one, 2024
• Early evidence of efficacy for orally administered SPM-enriched marine lipid fraction on quality of life and pain in a sample of adults with chronic pain Journal of translational medicine, 2020
• Online multimodal rehabilitation programme to improve symptoms and quality of life for adults diagnosed with long COVID-19: a Randomised Clinical Trial protocol Frontiers in public health, 2023
• The effect of co supplementation of omega-3 and vitamin D on cardio metabolic risk factors and psychological distress in reproductive-aged women with prediabetes and hypovitaminosis D: a study protocol for a randomized controlled trial Trials, 2019
• Assessment of Body Composition and Dietary Intake in Nursing-Home Residents: Could Lessons Learned from the COVID-19 Pandemic Be Used to Prevent Future Casualties in Older Individuals? Nutrients, 2021
• The evaluation of nightshade elimination diet (NED) on inflammatory and rheumatologic markers of rheumatoid arthritis patients: study protocol for a randomized controlled trial Trials, 2024
• The Association of Free Fatty Acids and Eicosanoids with the Severity of Depressive Symptoms in Stroke Patients International journal of molecular sciences, 2020
• Associations of Mediterranean diet with psychological ill-being and well-being throughout the pregnancy course: The GESTAFIT project Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2022
• Effect of targeted nutrient supplementation on physical activity and health-related quality of life in COPD: study protocol for the randomised controlled NUTRECOVER trial BMJ open, 2022
• Nutrition and movement to improve quality of life in patients with knee osteoarthritis: the NUMOQUA study protocol for a randomised controlled trial Trials, 2024
• Targeted dietary interventions to reduce pain in persistent post-traumatic headache among service members: Protocol for a randomized, controlled parallel-group trial Contemporary clinical trials, 2022
• The effect of bitter almond (Amygdalus communis L. var. Amara) gum as a functional food on metabolic profile, inflammatory markers, and mental health in type 2 diabetes women: a blinded randomized controlled trial protocol Trials, 2023
• Effects of a Remote Multimodal Intervention Involving Diet, Walking Program, and Breathing Exercise on Quality of Life Among Newly Diagnosed People with Multiple Sclerosis: A Quasi-Experimental Non-Inferiority Pilot Study Degenerative neurological and neuromuscular disease, 2024
• Biospecimens in the HEALthy Brain and Child Development (HBCD) Study: Rationale and protocol Developmental cognitive neuroscience, 2024
• The effect of omega-3 long chain polyunsaturated fatty acids on aggressive behaviour in adult male prisoners: a structured study protocol for a multi-centre, double-blind, randomised placebo-controlled trial and translation into policy and practice Trials, 2021
• Protocol for evaluating the effects of the Reducing Cardiometabolic Diseases Risk dietary pattern in the Chinese population with dyslipidaemia: a single-centre, open-label, dietary intervention study BMJ open, 2024
• Effects of intensive lifestyle changes on the progression of mild cognitive impairment or early dementia due to Alzheimer's disease: a randomized, controlled clinical trial Alzheimer's research & therapy, 2024
• Association between an oxidative balance score and mortality: a prospective analysis in the SUN cohort European journal of nutrition, 2023
• Multinutrients Decrease Oxidative Stress in Children With ADHD: Mediation/Moderation Analysis of Randomized Controlled Trial Data Journal of attention disorders, 2025
• The effects of a high eicosapentaenoic acid multinutrient supplement on measures of stress, anxiety and depression in young adults: Study protocol for NutriMOOD, a randomised double-blind placebo-controlled trial Prostaglandins, leukotrienes, and essential fatty acids, 2021
• Perioperative immunonutrition intervention on postoperative outcomes among gynecological cancer patients under enhanced recovery after surgery setting: A study protocol of explanatory mixed method study PloS one, 2024
• Sex-related differences and hormonal effects in the Dry Eye Assessment and Management (DREAM) study The British journal of ophthalmology, 2023
• Study protocol: fish oil supplement in prevention of oxaliplatin-induced peripheral neuropathy in adjuvant colorectal cancer patients - a randomized controlled trial. (OxaNeuro) BMC cancer, 2024
• Effectiveness of an anti-inflammatory diet versus low-fat diet for knee osteoarthritis: the FEAST randomised controlled trial protocol BMJ open, 2024
• Study protocol, menu design, and rationale for a study testing the effects of a whole fruit-rich diet on glycemic control, liver fat, pancreatic fat, and cardiovascular health in adults with type 2 diabetes Nutrition research (New York, N.Y.), 2025
• MCT-Induced Ketosis and Fiber in Rheumatoid Arthritis (MIKARA)-Study Protocol and Primary Endpoint Results of the Double-Blind Randomized Controlled Intervention Study Indicating Effects on Disease Activity in RA Patients Nutrients, 2023
• Food as medicine: a quasi-randomized control trial of two healthy food interventions for chronic disease management among ambulatory patients at an urban academic center Primary health care research & development, 2023
• A pragmatic randomized trial to examine the effect of combining healthy diet with mindfulness cognitive therapy to reduce depressive symptoms among university students in a low-resource setting: protocol for the NutriMind Project BMC psychiatry, 2024
• Efficacy of eicosapentaenoic acid in inflammatory depression: study protocol for a match-mismatch trial BMC psychiatry, 2022
• Effects of Spirulina platensis supplementation on quality of life, severity of disease and serum total antioxidant capacity, malondialdehyde and zonulin in constipation-predominant irritable bowel syndrome: protocol for a randomised, double-blinded, placebo-controlled clinical trial from Iran BMJ open, 2025
• KETO-MOOD: Ketogenic Diet for Microbiome Optimization and Overcoming Depression - A Protocol for a Randomized Controlled Trial Neuroimmunomodulation, 2025
• Acute effect of a Mediterranean-style dietary pattern (MDP) on mood, anxiety and cognition in UK adults with mild to moderate anxiety and depression: the MediMood randomised controlled trial protocol BMJ open, 2024
• Targeted Microbial Shifts and Metabolite Profiles Were Associated with Clinical Response to an Anti-Inflammatory Diet in Osteoarthritis Nutrients, 2025
• Study protocol to establish a prospective cohort for the study of phenotypic clusters, progression pathways, and outcomes of frailty and dependence: The CohorFES PloS one, 2026
• Effects of Walnuts on Postprandial Cognitive Function in Adults With Subjective Cognitive Impairment: Protocol for a Randomized Crossover Trial JMIR research protocols, 2025
• Neuroticism but not omega-3 fatty acid levels correlate with early responsiveness to escitalopram Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists, 2010
• Clinical effects of supplemental enteral nutrition solution in severe polytrauma Der Unfallchirurg, 1998
• An Exploratory Analysis of Changes in Mental Wellbeing Following Curcumin and Fish Oil Supplementation in Middle-Aged and Older Adults Nutrients, 2020
• The relationship between serum resolvin D1, NLRP3, cytokine levels, and adolescents with first-episode medication-naïve major depressive disorder BMC psychiatry, 2024
• Adjunctive low-dose docosahexaenoic acid (DHA) for major depression: An open-label pilot trial Nutritional neuroscience, 2018
• Omega-3/6 supplementation for mild to moderate inattentive ADHD: a randomised, double-blind, placebo-controlled efficacy study in Italian children European archives of psychiatry and clinical neuroscience, 2022
• Biological effects of add-on eicosapentaenoic acid supplementation in diabetes mellitus and co-morbid depression: a randomized controlled trial PloS one, 2012
• Association between blood polyunsaturated fatty acid levels and depressive symptoms in breast cancer survivors Prostaglandins, leukotrienes, and essential fatty acids, 2018
• Irritable eye syndrome: neuroimmune mechanisms and benefits of selected nutrients The ocular surface, 2014
• Eicosapentaenoic acid versus docosahexaenoic acid in mild-to-moderate depression: a randomized, double-blind, placebo-controlled trial European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2013
• Prevention of depression through nutritional strategies in high-risk persons: rationale and design of the MooDFOOD prevention trial BMC Psychiatry, 2016
• Comparison between the AA/EPA ratio in depressed and non depressed elderly females: omega-3 fatty acid supplementation correlates with improved symptoms but does not change immunological parameters Nutrix Journal, 2012
• Effects of n-3 fatty acids on depressive symptoms and dispositional optimism after myocardial infarction American Journal of Clinical Nutrition, 2011
• Effects of Fish Oil Monotherapy on Depression and Prefrontal Neurochemistry in Adolescents at High Risk for Bipolar I Disorder: A 12-Week Placebo-Controlled Proton Magnetic Resonance Spectroscopy Trial Journal of child and adolescent psychopharmacology, 2020
• Feasibility of Investigational Procedures and Efficacy of a Personalized Omega-3 Dietary Intervention in Alleviating Pain and Psychoneurological Symptoms in Breast Cancer Survivors Pain Management Nursing, 2022
• Effect of one year krill oil supplementation on depressive symptoms and self-esteem of Dutch adolescents: A randomized controlled trial Prostaglandins, Leukotrienes and Essential Fatty Acids, 2020
• Long chain omega 3 polyunsaturated fatty acids supplementation in the treatment of elderly depression: Effects on depressive symptoms, on phospholipids fatty acids profile and on health-related quality of life The Journal of Nutrition, Health & Aging, 2010