Browse studies, page 407
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- A Multicenter, Randomized, Double-Blind Study to Evaluate the Safety and Efficacy of MK0431 Monotherapy in Patients With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control ClinicalTrials.gov · COMPLETED, 2007
- The Effect of Calcium and Vitamin D Supplements as an Adjuvant Therapy to Metformin on Metabolic and Hormonal Disturbances in Polycystic Ovary Syndrome Patients ClinicalTrials.gov · COMPLETED, 2017
- A Phase 2 Trial of Paxalisib Combined With a Ketogenic Diet and Metformin for Newly Diagnosed and Recurrent Glioblastoma ClinicalTrials.gov · COMPLETED, 2026
- Comparison of Efficacy and Safety of Standard vs Higher Starting Dose of Insulin Glargine in Overweight and Obese Chinese Patients With Type 2 Diabetes ClinicalTrials.gov · COMPLETED, 2018
- Insulin Resistance and Mild Cognitive Impairment (MCI) in Older Chinese Adults With Pre-Diabetes and Diabetes: Cognitive Effects of Lifestyle Intervention and Metformin Treatment in a Randomized Controlled Trial ClinicalTrials.gov · TERMINATED, 2019
- Effects of ROSIglitazone on Inflammatory Markers and Adipokines in Diabetic Patients Using an Angiotensin Receptor Blocker (TELmisartan) - The ROSITEL Study ClinicalTrials.gov · COMPLETED, 2009
- Cinnamon Bark, Water-Soluble Cinnamon Extract, and Metformin as Initial Treatment for Type 2 Diabetes Mellitus: A Randomized, Controlled Trial ClinicalTrials.gov · TERMINATED, 2016
- Effect of Insulin Sensitizer Therapy on Atherothrombotic and Inflammatory Profiles Associated With Insulin Resistance ClinicalTrials.gov · COMPLETED, 2010
- A Randomized, Phase 3, Open-label Trial Comparing the Effect of Tirzepatide Once Weekly Versus Titrated Insulin Glargine on Glycemic Control in Patients With Type 2 Diabetes on Metformin With or Without a Sulfonylurea ClinicalTrials.gov · COMPLETED, 2021
- Effect of Green Tea Extract Administration on Arterial Stiffness in Patients With Type 2 Diabetes Mellitus ClinicalTrials.gov · COMPLETED, 2016
- Metformin Pharmacogenetics in Heart Failure Patients with Reduced Ejection Fraction: Impact on Metformin and Growth Differentiation Factor-15 Plasma Levels Clinical pharmacokinetics, 2026
- Metformin modulates survival, oxidative stress, and gene expression in a high-sucrose Drosophila diabetes model PloS one, 2026
- Metformin in Elderly Patients With Type 2 Diabetes and Muscle Strength, Muscle Mass, and Physical Function: Positive or Negative Correlation? International journal of endocrinology, 2026
- Pharmacokinetic and Pharmacodynamic Drug-Drug Interactions Between Cofrogliptin and Metformin in Healthy Subjects: A Single-Center, Single-Arm, Phase I Study in China Clinical pharmacology in drug development, 2026
- From seven combination hypotheses to one testable interaction: a gated agentic AI–QSP workflow applied to healthy-ageing interventions 2026
- Current Landscape in Clinical Drug Repurposing: From Non-Oncology Drugs to New Cancer Applications 2026
- Comparative Evaluation of Quality Attributes and In Vitro Dissolution Profile Similarity of Metformin Hydrochloride 500 mg Tablets Marketed in Sudan: Implications for Bioequivalence and Generic Interchangeability 2026
- Continuous Glucose Monitoring-Based Metrics with Fixed-Dose Combination Versus Co-administered Dapagliflozin/Metformin in Chinese Patients with Type 2 Diabetes Mellitus 2026
- Dose-Dependent Effect of Metformin Preconditioning on the Regenerative Potential of Human Umbilical Cord-Derived Mesenchymal Stem Cells: An In Vitro Experimental Study 2026
- Bacterial NDH-1 is a key gut target of metformin mediating its antidiabetic effects 2026
- Current understanding of metformin effect on the control of hyperglycemia in diabetes The Journal of endocrinology, 2016
- Metformin and Prostate Cancer: a New Role for an Old Drug Current urology reports, 2017
- The effect of metformin on glucose metabolism in patients receiving glucocorticoids The American journal of the medical sciences, 2022
- Metformin suppresses pro-inflammatory cytokines in vitreous of diabetes patients and human retinal vascular endothelium PloS one, 2022
- Impact of metformin treatment on cobalamin status in persons with type 2 diabetes Nutrition reviews, 2024
- Repositioning metformin in cancer: genetics, drug targets, and new ways of delivery Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2014
- Trial of restarting and tolerating metformin (TreatMet) Diabetes, obesity & metabolism, 2020
- Metformin and retinal diseases in preclinical and clinical studies: Insights and review of literature Experimental biology and medicine (Maywood, N.J.), 2022
- Role of renin angiotensin system inhibitors and metformin in Glioblastoma Therapy: a review Cancer chemotherapy and pharmacology, 2024
- Metformin-mediated amelioration of the ovarian microenvironment in autoimmune premature ovarian insufficiency Biochemical and biophysical research communications, 2025
- Involvement of glucagon-like peptide-1 in the glucose-lowering effect of metformin Diabetes, obesity & metabolism, 2016
- Metformin Nanodelivery System Alleviates Morphine-Induced Analgesic Tolerance via Inhibiting the TXNIP/NLRP3/GSDMD Axis ACS applied bio materials, 2025
- Comprehensive analysis of metformin-associated lactic acidosis: Insights from the FDA Adverse Event Reporting System (FAERS) Medicine, 2025
- Current understanding of the pharmacogenomics of metformin Clinical pharmacology and therapeutics, 2009
- Metformin's Impact on the Microvascular Response to Insulin Endocrinology, 2022
- Targeting UXS1-Dependent Glucuronate Detoxification Potentiates Metformin's Anti-Tumor Efficacy in Lung Adenocarcinoma Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026
- Beyond diabetes: harnessing the power of metformin in burn care Critical care (London, England), 2025
- Injectable and pH-Responsive Metformin-Loaded Hydrogel for Active Inhibition of Posterior Capsular Opacification ACS applied materials & interfaces, 2024
- Metformin - its potential anti-cancer and anti-aging effects Postepy higieny i medycyny doswiadczalnej (Online), 2017
- Antiproliferative effects of metformin in cellular models of pheochromocytoma Molecular and cellular endocrinology, 2022
- Metformin and Angiogenesis in Cancer - Revisited Oncology, 2016
- Mechanisms of action of metformin with special reference to cardiovascular protection Diabetes/metabolism research and reviews, 2019
- Novel therapeutic targets of metformin: metabolic syndrome and cardiovascular disease Expert opinion on therapeutic targets, 2015
- Metformin in Esophageal Carcinoma: Exploring Molecular Mechanisms and Therapeutic Insights International journal of molecular sciences, 2024
- Metformin and Chemoprevention: Potential for Heart-Healthy Targeting of Biologically Aggressive Breast Cancer Frontiers in public health, 2020
- The Research Progress of Metformin Regulation of Metabolic Reprogramming in Malignant Tumors Pharmaceutical research, 2024
- Metformin and cancer: Between the bioenergetic disturbances and the antifolate activity Pharmacological research, 2015
- Novel mechanism whereby metformin improves glucose homeostasis: TXNIP-GLUT1 axis modulation enhances intestinal glucotonic effects Experimental & molecular medicine, 2025
- Repurposing of Metformin for Cancer Therapy: Updated Patent and Literature Review Recent patents on anti-cancer drug discovery, 2021
- Metformin derivatives - Researchers' friends or foes? Biochemical pharmacology, 2023
- The Role and Mechanism of Metformin in the Treatment of Nervous System Diseases Biomolecules, 2024
- Metformin inhibition of glycation processes Diabetes & metabolism, 2003
- Metformin and Adipose Tissue: A Multifaceted Regulator in Metabolism, Inflammation, and Regeneration Endocrinology and metabolism (Seoul, Korea), 2025
- Metformin, Microbiome and Protection Against Colorectal Cancer Digestive diseases and sciences, 2021
- Metformin: Metabolic Rewiring Faces Tumor Heterogeneity Cells, 2020
- An anti-neoplastic tale of metformin through its transport Life sciences, 2024
- Metformin and HER2-positive breast cancer: Mechanisms and therapeutic implications Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023
- Mechanisms of action of metformin in type 2 diabetes: Effects on mitochondria and leukocyte-endothelium interactions Redox biology, 2020
- Metformin and Breast Cancer: Molecular Targets Journal of mammary gland biology and neoplasia, 2019
- Metformin and gynecologic cancers Obstetrical & gynecological survey, 2014
- Cardioprotective Effects of Metformin Journal of cardiovascular pharmacology, 2018
- Genetically Proxied Therapeutic Effect of Metformin Use, Blood Pressure, and Hypertension's Risk: a Drug Target-Based Mendelian Randomization Study Journal of cardiovascular translational research, 2024
- Metformin alters mitochondria-related metabolism and enhances human oligodendrocyte function Nature communications, 2025
- Metformin attenuates colitis via blocking STAT3 acetylation by reducing acetyl-CoA production Journal of advanced research, 2026
- Metformin suppresses vascular smooth muscle cell senescence by promoting autophagic flux Journal of advanced research, 2022
- Entwicklung und Charakterisierung eines trojanischen Helicobacter pylori RWTH Publications (RWTH Aachen), 2026
- Artificial Intelligence: An Emerging Tool for Studying Drug‐Induced Liver Injury Liver International, 2025
- Circadian Modulation of Enterohepatic Circulation: Time-Varying Delay Analysis in Two-Compartment Pharmacokinetic Control 2025
- In-Silico Investigation of the Anti-Ulcer Potentials of Ethanolic Extract of Chromolaena Odarata International Journal of Educational and Life Sciences, 2024
- Computational Screening of FDA‐Approved PPIs and PCABs against LasR Protein: Insights into Quorum Sensing Inhibition ChemistrySelect, 2025
- Structural Basis for Binding of Potassium-Competitive Acid Blockers to the Gastric Proton Pump Journal of medicinal chemistry, 2022
- CYP2C19 Loss‐of‐Function Is an Independent Risk Factor of Coronary Artery Disease in Patients With Hypertension Journal of Clinical Laboratory Analysis, 2025
- CYP2C19 loss-of-function is associated with increased risk of hypertension in a Hakka population: a case-control study BMC Cardiovascular Disorders, 2023
- Effect of Acid Suppressants on Adverse Events of Immune Checkpoint Inhibitors Using Real-world Databases Anticancer Research, 2025
- Herbal plants and their antimicrobial role in oral health: a comprehensive review BOHR Journal of Pharmaceutical Studies., 2026
- Design of vonoprazan pyrazole derivatives as potential reversible inhibitors of gastric proton pump: An in silico molecular docking study AFMN Biomedicine, 2023
- Rabeprazole attenuates fibrosis by modulating SMAD3 linker region phosphorylation Biomedical Reports, 2025
- Comparison of Pharmacokinetic, Pharmacodynamic and Tolerability Profiles of CKD-11101, Darbepoetin Alfa (NESP®) Biosimilar, to Those of NESP® After a Single Subcutaneous or Intravenous Administration to Healthy Subjects Drug Design Development and Therapy, 2021
- Neuroendocrine mechanism of gastric acid secretion: Historical perspectives and recent developments in physiology and pharmacology Journal of Neuroendocrinology, 2023
- A pilot study on the effect of video games on ASD children's mental health and behaviour and oral health management in Syria – 2023 Oral & Implantology, 2025
- Tratamiento farmacológico de la enfermedad por reflujo gastroesofágico Clínicas de gastroenterología de México, 2025
- Insights into amoxicillin pharmacokinetics using physiology-based pharmacokinetic modelling Antimicrobial Agents and Chemotherapy, 2026
- Therapeutic potential of Asiaticoside in wound healing after endoscopic submucosal dissection (ESD) Pharmaceutical Biology, 2026
- Randomised clinical trial: Safety, tolerability, pharmacodynamics and pharmacokinetics of zastaprazan (JP-1366), a novel potassium-competitive acid blocker, in healthy subjects Alimentary Pharmacology & Therapeutics, 2023
- Model-Based Prediction of Acid Suppression and Proposal of a New Dosing Regimen of Fexuprazan in Humans Pharmaceuticals, 2022
- Population pharmacokinetic analysis of zastaprazan (JP-1366), a novel potassium-competitive acid blocker, in patients and healthy volunteers CPT Pharmacometrics & Systems Pharmacology, 2024
- Identification of Novel Antibacterials Using Machine Learning Techniques Frontiers in Pharmacology, 2019
- Comparative Efficacy of Vonoprazan and Proton Pump Inhibitors in Gastrointestinal Ulcer Healing and Post-ESD Bleeding Prevention medtigo Journal of Medicine, 2025
- Evaluation of drug-drug interaction potentials between JP-1366 and celecoxib using physiologically based pharmacokinetic modeling Translational and Clinical Pharmacology, 2025
- Prediction of the Drug–Drug Interaction Potential between Tegoprazan and Amoxicillin/Clarithromycin Using the Physiologically Based Pharmacokinetic and Pharmacodynamic Model Pharmaceuticals, 2023
- OCLI-023, a Novel Pyrimidine Compound, Suppresses Osteoclastogenesis In Vitro and Alveolar Bone Resorption In Vivo PLoS ONE, 2017
- Dietary lysophospholipids supplementation inhibited the activity of lipolytic bacteria in forage with high oil diet: an in vitro study Asian-Australasian Journal of Animal Sciences, 2020
- Enhanced Dissolution and Oral Bioavailability of Tegoprazan Using D-α-Tocopheryl Polyethylene Glycol 1000 Succinate-Based Melt Granulation System Molecules, 2026
- Deep learning driven de novo drug design based on gastric proton pump structures Communications biology, 2023
- Impact of diabetes and prediabetes on dental implant success: a comprehensive review Oral & Implantology, 2024
- Deciphering internal and external factors influencing intestinal junctional complexes Gut Microbes, 2024
- Sex and Gender Differences in Peptic Ulcer Disease: A Scoping Review with Exploratory Quantitative Synthesis for Clinical Guideline Development Gut and Liver, 2026
- The role of metal ions in the occurrence, progression, drug resistance, and biological characteristics of gastric cancer Frontiers in Pharmacology, 2024
- The Ion Channels Involved in Oxidative Stress-Related Gastrointestinal Diseases Oxygen, 2023
- Association between Proton Pump Inhibitor Use and the Risk of Female Cancers: A Nested Case-Control Study of 23 Million Individuals Cancers, 2022
