Evidence Hub

Differential Privacy Synthetic Tabular Data Generation for Federated Learning

Almató-Baucells M, Lázaro C, Angulo C

2026

Abstract

Machine learning in healthcare struggles for one main reason: good data is hard to come by. Medical records are sensitive, and the rules on sharing them between hospitals are strict. A common workaround is synthetic data, that is artificial records that copy the statistics of real ones; however, on its own, it offers no real privacy guarantee, and earlier studies show it can still leak details about the patients behind it. We introduce an approach tackling both problems at once. It builds on a previous UMAP-based generator methodology and extends it so several hospitals can work together without sharing raw records, in a federated learning form. Then, the proposed methodology adds differential privacy so every shared quantity carries a formal (εDP,δ) guarantee, tracked by a custom privacy accountant. Two versions of the methodology are tested: a partially synthetic one, where a reference hospital validates the others’ rows, and a fully synthetic one, where each centre builds its own data from aggregated cluster statistics. Both are evaluated on four publicly available healthcare tabular datasets spanning prostate cancer (PI-CAI, CIA), breast cancer (BC-MLR), and cardiovascular disease (fiv-CardioDB), to test whether the observed trends generalize beyond a single clinical domain. As a key takeaway, it is demonstrated that going federated barely affects quality, but the privacy cost depends strongly on the moment in the procedure when the noise is injected, and this pattern…

Read the paper

Related studies

Go deeper in Evidence Hub

Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.

Open this study Sign up free