The impact of sildenafil on molecular science and sexual health
Abstract
OBJECTIVE: Sexual medicine has evolved greatly in the past several years, to a large extent because of the introduction of the phosphodiesterase-5 (PDE5) inhibitor, Viagra (sildenafil citrate), as a highly effective oral therapy for erectile dysfunction.
METHODS: Recent literature pertaining to the development and clinical applications of sildenafil citrate was reviewed.
RESULTS: The emergence of PDE5 inhibitor therapy for erectile dysfunction represents a major scientific and clinical breakthrough, and it has impacted on the field in such prominent areas as scientific discovery, clinical management, and public health awareness of sexual health disorders.
CONCLUSION: The development of sildenafil citrate has had a major role in advancing the field of sexual medicine.
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