Effect of sildenafil on resting and exercise haemodynamics in hypoxia in patients with pulmonary vascular diseases: data from a randomised controlled trial
Abstract
In patients with PH exposed to simulated ∼2500-m hypoxia, a single 50-mg sildenafil dose had no effect at rest but reduced exercise-induced pulmonary pressure and resistance, potentially improving exercise capacity during hypoxic exposure https://bit.ly/4rHhvFz.
How strong is the evidence?
Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design.
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