Sildenafil for Fontan Associated Liver Disease (SiFALD) Study
Abstract
The purpose of this study is to determine if the medication, sildenafil (also known as Revatio), can slow or stop the progression of liver disease in patients who previously had a Fontan operation.
Conditions: Cirrhosis, Congenital Heart Disease.
Primary outcome: Liver Stiffness as Measured by Magnetic Resonance Elastography (MRE).
Enrollment: 20 participants.
How strong is the evidence?
Evidence Hub reads this as a clinical trial, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence. Reported size: 20 participants or records.
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