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Sildenafil for Severe Lymphatic Malformations

Glenda L. Swetman, David R. Berk, Shreyas S. Vasanawala, Jeffrey A. Feinstein, Alfred T. Lane, Anna L. Bruckner

New England Journal of Medicine, 2012

145 citations

Abstract

Lymphatic malformations are rare but can cause significant clinical problems in addition to cosmetic disfigurement. Sildenafil was used in a child whose pulmonary hypertension was caused by lymphatic malformation; the result was a marked decrease in the lymphatic malformation.

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