Evidence Hub

Intracerebral hemorrhage associated with use of sildenafil: case report

Hugo Rico-Hernández, Vanessa Cano-Nigenda, Charles A. Huamaní-Saldaña, Ángel Arauz, Andrés A. Mercado-Pompa

Archivos de Neurociencias (English ed ), 2025

Abstract

Intracerebral hemorrhage results from the degeneration of penetrating arterioles in the brain parenchyma.This report presents the case of a 47-year-old man who experienced a hemorrhagic stroke with a direct temporal relationship to sildenafil consumption.A computed tomography (CT) scan confirmed a cerebellar hemorrhage predominantly involving the vermis and the left hemisphere.Hemorrhage associated with sildenafil use is an extremely rare phenomenon.Its causative relationship can only be considered after ruling out more common etiologies, such as hypertension, cerebral amyloid angiopathy, or aneurysms.Moreover, sildenafil could only be classified as a causative agent if it was ingested within two hours prior to symptom onset.

How strong is the evidence?

Evidence Hub reads this as a case report, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.

How the five levels of evidence work. The level is assigned automatically from the abstract and can be wrong, so check the paper.

Read the paper

Related studies

Go deeper in Evidence Hub

Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.

Open this study Sign up free