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Neurodevelopmental Outcomes at 2 Years in Children Who Received Sildenafil Therapy In Utero: The STRIDER Randomized Controlled Trial

Andrew Sharp, Christine Cornforth, Richard J. Jackson, J. Harrold, Mark Turner, L. Kenny, Philip N. Baker, E. Johnstone et al.

Obstetrical & Gynecological Survey, 2025

Abstract

(Abstracted from BJOG 2024;131:1673–1683)

Fetal growth restriction (FGR) occurs when a fetus grows slower than expected for gestational age. Severe early-onset cases are associated with stillbirth, neonatal death, and developmental disorders.

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Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design.

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