A Neonate with Kluyvera Sepsis: A Case Report
Abstract
The genus name Kluyvera species was first described in 1936 by Kluyvera et al[1]. Until recently, they were believed to be saprophytic non-pathogenic microorganisms, but latest studies indicated that serious clinical infections such as bacteremia, soft tissue infections, intraabdominal abscess and urinary tract infections may occur[2, 3]. So, recognition of the disease and its potentials along with the antibacterial spectrum in neonatal population is important to start an effective treatment and to reduce morbidity and mortality.
An eight-day-old boy with hypoglycemia and thrombocytopenia was referred to our NICU for further investigation and treatment (birth weight: 2500 g). On day 5 of life, he was immediately hospitalized in the medical center with the complaint of poor feeding and cyanosis. He was treated with ampicillin and amikasin for suspected sepsis. On the third day of admission, vancomycin and meropenem were initiated since clinical condition did not improve with prior therapy.
Physical examination revealed an evidently sick boy with a pulse rate of 152/min, respiration rate 54/min, blood pressure 120/80 mmHg, temperature 36.9°C, oxygen saturation 95%. The rest of the physical examination was unremarkable. Abnormal laboratory findings showed the following results: platelet count 38000/L, C-reactive protein 94.8 mg/L. Blood culture and urine culture were taken and vancomycin and meropenem continued at the previously initiated dose. Cranial ultrasound showed no sign…
How strong is the evidence?
Evidence Hub reads this as a case series, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health. Reported size: 15 participants or records.
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