Acute Unilateral Iris Transillumination Following Topical Moxifloxacin: A Case Report and Anterior Segment Optical Coherence Tomography Findings
Abstract
Purpose: To describe the anterior segment swept-source optical coherence tomography (AS-SS OCT) findings of the iris in a patient with unilateral acute iris transillumination associated with iris depigmentation following topical moxifloxacin treatment for corneal trauma.
Methods: Case report.
Results: AS-SS-OCT imaging of the affected iris showed loss of the normal hyperreflective anterior iris border in both the pupillary and ciliary portions. The stromal layer appeared thinned, with patchy clusters of hyperreflective dots throughout the stroma. The homogeneous and poorly defined hyperreflectivity of the iris pigment epithelium was attenuated or completely absent in the most clinically affected areas, allowing light transmission.
Conclusions: AS-SS-OCT imaging demonstrates a distinctive pattern of iris involvement in unilateral acute iris transillumination (UAIT), which, in conjunction with clinical findings, may aid in diagnosis and reveal features overlapping with a BAIT-like phenotype, supporting its role as a valuable diagnostic tool in this entity.
How strong is the evidence?
Evidence Hub reads this as a case report, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.
Read the paper
Related studies
- Synthesis, In Vitro and In Silico Molecular Docking Studies of Novel Phthalimide–Pyrimidine Hybrid Analogues to Thalidomide as Potent Antitubercular Agents
- Exploring the inhibitory performance of expired moxifloxacin and norfloxacin on copper corrosion in saline environment
- Molecular investigation of antimicrobial peptides against Helicobacter pylori proteins using a peptide-protein docking approach
- Screening of novel narrow-spectrum benzofuroxan derivatives for the treatment of multidrug-resistant tuberculosis through in silico, in vitro, and in vivo approaches
- Synthesis, Characterization, Anticancer, Antioxidant, and In Silico Evaluation of Semicarbazides and Thiosemicarbazides
- Fast and accurate prediction of drug induced proarrhythmic risk with sex specific cardiac emulators
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.