Quinolone Antibiotics: The Development of Moxifloxacin
Abstract
This chapter contains sections titled: Introduction Aims The Chemical Evolution of Moxifloxacin Synthetic Routes S,S–2,8-Diazabicyclo[4.3.0]nonane Preparation of BAY X 8843 36 and its Analogues Preparation of Moxifloxacin Hydrochloride 47 The Physicochemical Properties of Moxifloxacin The Microbiological and Clinical Properties of Moxifloxacin Mycobacterium tuberculosis Skin Infections Ophthalmology Dental Medicine Pharmacokinetics/Pharmacodynamics of Moxifloxacin Development of Resistance to Moxifloxacin Safety and Tolerability of Moxifloxacin Metabolism, Excretion and Biodegradability of Moxifloxacin Future Prospects for Quinolones Summary and Conclusions
Read the paper
Related studies
- Synthesis, In Vitro and In Silico Molecular Docking Studies of Novel Phthalimide–Pyrimidine Hybrid Analogues to Thalidomide as Potent Antitubercular Agents
- Exploring the inhibitory performance of expired moxifloxacin and norfloxacin on copper corrosion in saline environment
- Molecular investigation of antimicrobial peptides against Helicobacter pylori proteins using a peptide-protein docking approach
- Screening of novel narrow-spectrum benzofuroxan derivatives for the treatment of multidrug-resistant tuberculosis through in silico, in vitro, and in vivo approaches
- Synthesis, Characterization, Anticancer, Antioxidant, and In Silico Evaluation of Semicarbazides and Thiosemicarbazides
- Fast and accurate prediction of drug induced proarrhythmic risk with sex specific cardiac emulators
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.