A meta analysis of the efficacy and safety of moxifloxacin in Chinese patients with multi-drug resistant pulmonary tuberculosisosis
Abstract
2 = 0%). The results of meta-analysis showed that compared with the control group, moxifloxacin was more effective in sputum negative conversion (OR = 3.34, 95% CI: 2.37 to 4.70) and focus absorption (OR = 2.53, 95% CI: 1.55 to 4.12). Moreover, moxifloxacin was safer than control group (OR = 0.73, 95% CI: 0.55 to 0.96). Funnel-plot displayed some unsymmetrical figures, indicating there were publication biases in each analysis. The evidence currently available shows that the moxifloxacin treatment on Chinese patients with MDR-TB is useful for the sputum negative conversion and focus absorption.
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