Incidence of intraocular lens (IOL) tilt and decentration after secondary IOL sulcus implantation versus optic capture in pediatric aphakia
Abstract
Purpose: To compare the tilt and decentration between secondary sulcus-implanted versus optic-captured intraocular lens (IOL) in pediatric aphakia using ultrasound bio-microscopy (UBM).
Design: Prospective, comparative study at "Cairo University" pediatric ophthalmology and strabismus unit.
Methods: Forty-four eyes of 25 aphakics were scheduled for secondary implantation. Patients were randomly divided into two equal groups: Group A underwent sulcus implantation, while Group B underwent optic capture. UBM was performed preoperatively, 3 months and 6 months after surgery to evaluate the anterior chamber depth (ACD), angle width in the four quadrants, horizontal and vertical tilt, and decentration.
Results: Preoperative demographic data, ACD, and angle width did not differ between the groups. Six months after surgery, ACD was significantly higher in the capture group (mean 3.6 mm ± 0.59 [2.25-4.45]) than the sulcus group (mean 3.01 mm ± 0.25 [2.55-3.33]) with a mean difference of 0.59 mm (P = 0.000). The anterior chamber angle (ACA) showed larger values in all four quadrants in the capture group, highly statistically significant in the temporal (47.09° versus 42.23° P = 0.001) and superior (46.38° versus 42.47° P = 0.009) quadrants. Although there was no difference in the horizontal (0.22 versus 0.31 mm) and vertical (0.28 versus 0.30 mm) decentration between both groups, the capture group showed statistically significant more horizontal (1.8 versus 0.83°) and vertical tilt…
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Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design.
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