A prospective study to compare the safety and efficacy of toric intra-ocular lens vs. opposite clear corneal incision in patients undergoing phacoemulsification for age-related cataract with pre-existing corneal astigmatism
Abstract
Purpose: This study aimed to compare the safety and efficacy of toric intra ocular lens (IOL) implantation vs. opposite clear corneal incision (OCCI) during cataract surgery to correct preexisting corneal astigmatism in patients with age related cataract by comparing the postoperative residual astigmatism, the uncorrected distance visual acuity and the adverse effects following both the procedures.
Methods: A pilot prospective study was conducted at a tertiary hospital among patients undergoing cataract surgery over two years. A total of 150 eyes with pre-existing corneal astigmatism between 1 to 2.5 D were divided into two groups of 75 each by permuted block randomization. Group A underwent implantation of AcrySof Toric IOLSN6AT4 (Alcon Labs, Fort Worth, Tx), and Group B underwent implantation of normal non-toric aspheric AcrySof IOL SN60WF with OCCI on steep axis. Both groups were followed up for 24 weeks.
Results: In the OCCI Group, the difference between mean K1-K2 preoperative and 12 weeks postoperative (mean ± SD) of patients was 1.55 ± 0.17D. In the TORIC IOL Group, the difference between the mean K1-K2 preoperative and 12-week postoperative values (mean ± SD) for patients was 0.53 ± 0.11. The difference in mean K1-K2 pre-operatively and at 12 weeks was statistically significant for both groups (p < 0.0001). There was a significant reduction in corneal astigmatism in the OCCI group at 01 week.
Discussion: In our study, the difference in mean K1-K2 at 1 week between…
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Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design.
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