Long-term outcomes of lamellar crescentic wedge resection on corneal astigmatism and optical aberrations in patients with advanced pellucid marginal degeneration
Abstract
Background/aim: The present study investigates the long-term changes in corneal astigmatism and aberrations following lamellar wedge resection in cases with advanced pellucid marginal degeneration (PMD).
Materials and methods: Patients with advanced PMD whose visual acuity did not improve with glasses or contact lenses underwent lamellar crescentic wedge resection. Pre- and postoperative assessments at 3, 6, 12, and 24 months using Pentacam HR were conducted to identify changes in corrected visual acuity, corneal astigmatism, and higher-order aberrations (HOAs) following the procedure, and compared with a control group.
Results: Statistically significant postoperative improvements in corrected visual acuity were observed at 6 and 12 months compared to preoperative values. At postoperative 3, 6, 12, and 24 months, significant improvements from preoperative values were noted in logMAR, astigmatism, and Kmax parameters (p < 0.05). A comparison of the patients with PMD and a control group revealed significant postoperative reductions in anterior and posterior coma, trefoil, spherical, and tetrafoil aberrations at 4 mm and 6 mm (p < 0.05). Most parameters remained statistically different from the healthy controls, indicating improvement without complete normalization. Although no significant difference was noted in the 6 mm anterior root mean square (RMS) value, a statistically significant reduction was observed in the 6 mm posterior RMS value at postoperative 3 and 6 months (p <…
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