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Refractive and Visual Outcomes of SmartSight NOVA Refractive Lenticule Extraction for Myopia and Myopic Astigmatism at 3 Months: a Retrospective Case Series

Keum JE, Yoo TK, Kim JC, Kim JH

Ophthalmology and therapy, 2026

42 participants · 1 citation

Abstract

Introduction: SmartSight NOVA using the ATOS platform (SCHWIND eye-tech-solutions GmbH, Kleinostheim, Germany) is a refractive lenticule extraction method with CenTrax-assisted centration. We hypothesized that SmartSight NOVA would provide safe, effective, and predictable 3-month outcomes for myopia and myopic astigmatism while maintaining favorable positional stability relative to the preoperative vertex-centered reference and acceptable higher-order aberration profiles.

Methods: This retrospective single-center case series included 84 eyes of 42 patients treated with SmartSight NOVA for myopia and myopic astigmatism. Standard refractive surgery outcome analyses were performed at 1 and 3 months, including visual acuity, manifest refraction, and stability. Higher-order aberrations, chord μ subgroup analyses, and postoperative center-coordinate stability relative to the preoperative position were also assessed.

Results: No clinically significant intraoperative or postoperative complications were observed during the 3-month follow-up. Preoperative manifest spherical equivalent was -3.70 ± 1.21 D. At 3 months, mean postoperative uncorrected distance visual acuity was 0.006 ± 0.020 logarithm of the minimum angle of resolution (logMAR), and postoperative manifest sphere, cylinder, and spherical equivalent were 0.021 ± 0.311 D, -0.327 ± 0.280 D, and -0.143 ± 0.336 D, respectively. Spherical equivalent was within ± 0.50 diopters (D) in 81.0% of eyes at 1 month and 89.3% at 3…

How strong is the evidence?

Evidence Hub reads this as a case series, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health. Reported size: 42 participants or records.

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