Retrospective analysis of indications and outcomes of trabecular micro-bypass stent implantation in Indian eyes
Abstract
Purpose: To analyze the patient characteristics, initial outcomes, and complications associated with iStent implantation in Indian eyes.
Methods: This retrospective case series comprised subjects who underwent iStent, iStent inject, or iStent inject W implantation as a standalone procedure or combined with phacoemulsification with at least 12 months follow-up. The main outcome measures were change in intraocular pressure (IOP) and number of anti-glaucoma medication (AGM), post op complications, and resurgery rates at the final follow-up.
Results: A total of 56 eyes of 46 patients were included. Twenty-six eyes received iStent, and 30 eyes received either iStent inject or iStent inject W. Mean IOP reduced by 25.5%, and the mean number of AGM decreased by 75.8% at final follow-up ( P < 0.005). The overall success rate was achieved in 51 eyes (85%). When compared to standalone iStent, combined phacoemulsification with iStent delivered greater reduction in AGM ( P = 0.004). Compared to iStent, eyes with iStent inject and inject W had better IOP reduction ( P = 0.03), lesser AGM ( P < 0.005), and a lesser number of surgical failures ( P = 0.045). Three months after iStent inject implantation, trabeculectomy was performed in one eye with secondary glaucoma. Postoperative IOP rise due to steroid response was observed in 20 eyes (35.7%).
Conclusion: iStent implantation in Indian eyes demonstrated promising outcomes in reducing both intraocular pressure and anti-glaucoma medication…
How strong is the evidence?
Evidence Hub reads this as a case series, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health. Reported size: 46 participants or records.
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