Effects of Topical Bromfenac Solution on Macular Thickness in Cataract Patients Undergoing Phacoemulsification Surgery
Abstract
Background Although modern phacoemulsification is considered a highly safe surgery, cystoid macular edema (CME) is the common factor contributing to poor visual results following successful surgery. Bromfenac drops may be effective in treating both acute and chronic pseudophakic CME. Objectives Evaluate the effects of the non–steroidal anti-inflammatory drug bromfenac 0.09% ophthalmic solution on macular thickness after phacoemulsification surgery and report any side effects. Method This is a prospective study done in an ophthalmic center in Iraq involving adult patients with senile or iatrogenic cataracts prepared for cataract surgery by phacoemulsification with intraocular lens (IOL) implantation and were divided into two groups: • Group one: who received 0.09% bromfenac ophthalmic solution twice daily in addition to Moxifloxacin 0.5% ophthalmic drops every 6hrs and Dexamethasone phosphate 0.1% ophthalmic drops every 4-6hrs post-operatively. • Group two: who received only Moxifloxacin 0.5% every 6 hours and Dexamethasone phosphate 0.1% ophthalmic drop every 4-6 hours without administering bromfenac 0.09% ophthalmic drops post-operatively. Results Eighty-seven eyes of 87 patients were enrolled in the study. The preoperative mean of central retinal thickness in groups one and two was 248.53±35.6μm and 262.40±20.7μm, respectively, with a p-value of 0.029. The postoperative mean of central retinal thickness in groups one and two was 255.78±36.6 μm and 278.18±29.06 μm,…
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