Comparison of Postoperative Intraocular Inflammation in Dogs Receiving Transzonular Intravitreal Triamcinolone-Moxifloxacin Versus Subconjunctival Triamcinolone After Phacoemulsification
Abstract
OBJECTIVE: To evaluate the postoperative effect of transzonular intravitreal triamcinolone-moxifloxacin compared to subconjunctival triamcinolone administered during phacoemulsification in dogs.
ANIMALS STUDIED: Forty-eight dogs (96 eyes) undergoing bilateral phacoemulsification and intraocular lens implantation.
PROCEDURES: All dogs undergoing phacoemulsification and intraocular lens implantation received transzonular intravitreal triamcinolone-moxifloxacin (TITM) in one eye and subconjunctival triamcinolone (SCT) in the contralateral eye. Aqueous flare (AF), anterior chamber fibrin formation (FF), pigment precipitates (PP) on the intraocular lens, posterior capsular opacification (PCO), corneal edema (CE), and intraocular pressure (IOP) were assessed 1 day, 1 week, 2-3 weeks, 4-6 weeks, 8-12 weeks, and ≥ 3 months postoperatively.
RESULTS: There was no difference in AF over time (p > 0.05); however, at 2-3 weeks postoperatively, the average AF was statistically greater (p = 0.01) in the TITM group compared to the SCT group. At three postoperative time points, IOP was significantly different (p < 0.05) between TITM and SCT eyes, but remained within a normal reference range. In both groups, IOP significantly decreased (p < 0.05) over time.
CONCLUSIONS: In the parameters evaluated, including overall visual outcome and surgical success, no clinically relevant differences between groups were appreciable. TITM and SCT, used adjunctively to postoperative topical ophthalmic and…
Read the paper
Related studies
- Synthesis, In Vitro and In Silico Molecular Docking Studies of Novel Phthalimide–Pyrimidine Hybrid Analogues to Thalidomide as Potent Antitubercular Agents
- Exploring the inhibitory performance of expired moxifloxacin and norfloxacin on copper corrosion in saline environment
- Molecular investigation of antimicrobial peptides against Helicobacter pylori proteins using a peptide-protein docking approach
- Screening of novel narrow-spectrum benzofuroxan derivatives for the treatment of multidrug-resistant tuberculosis through in silico, in vitro, and in vivo approaches
- Synthesis, Characterization, Anticancer, Antioxidant, and In Silico Evaluation of Semicarbazides and Thiosemicarbazides
- Fast and accurate prediction of drug induced proarrhythmic risk with sex specific cardiac emulators
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.