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Management of Retinopathy of Prematurity in the United Arab Emirates: A Consensus Statement From the Emirates Society of Ophthalmology

Al Ali AK, Al Qassimi N, Al Shamsi H, Ali SMA, Kar Ms T, Obaid L, Sukhi F, Al Hasid HS et al.

Cureus, 2026

Abstract

Retinopathy of prematurity (ROP) is a leading cause of preventable childhood blindness worldwide and affects a substantial proportion of very preterm or very-low-birth-weight infants. In the United Arab Emirates (UAE), hospital-based cohorts report a notable incidence of ROP among preterm infants, underscoring the need for standardized protocols. This Nominal Group Technique (NGT)-based national expert consensus aims to provide unified guidance for early detection, effective management, and improved outcomes for infants at risk of ROP in the UAE. A nationally representative panel of UAE-based consultant ophthalmologists, with neonatologists as non-voting advisors, developed recommendations for the International Classification of Retinopathy of Prematurity, Third Edition (ICROP-III) classification, screening, and management. Key management strategies include timely laser photocoagulation for treatment-requiring ROP, where feasible, and intravitreal anti-vascular endothelial growth factor (VEGF) therapy as a preferred or initial option in posterior disease and aggressive ROP (A-ROP), with prolonged surveillance for reactivation. Unmet needs include system-level gaps (standardized documentation, integrated tracking, and follow-up pathways) and educational gaps, particularly neonatologist and neonatal intensive care unit (NICU) staff engagement in prevention and long-term follow-up.

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