A comparison of the efficacy of tadalafil and sildenafil in the treatment of erectile dysfunction in men with combat-related injuries
Abstract
Erectile dysfunction (ED) is primarily defined as the inability to achieve and maintain an adequate erection for satisfactory sexual intercourse. The causes of sexual dysfunction in combat veterans are multifactorial and result from a complex interplay of physical, physiological, psychological, and social factors, among others. First-line therapy for most men with erectile dysfunction involves the oral administration of type 5 phosphodiesterase inhibitors. The aim of this study was to analyze the efficacy of tadalafil and sildenafil in treating erectile dysfunction in men with combat-related trauma. The study was based on the results of the examination and treatment of 54 men aged 20–53 years, combat veterans, with sexual dysfunction and erectile dysfunction as their primary complaint. Group 1 consisted of 26 patients who received tadalafil (20 mg) and group 2 consisted of 28 patients who received sildenafil citrate (100 mg) regularly as needed over the course of one month. As a result of treating male erectile dysfunction with tadalafil and sildenafil, all ED-IIEF-5 scores improved significantly. The IIEF-5 scores in both groups after treatment were significantly better than before treatment. Thus, with tadalafil treatment, the mean score increased from 13.2±2.8 to 20.2 ± 2.1 (P = 0.05), and with sildenafil treatment, it increased from 13.2 ± 2.8 to 22.4 ± 3.2 (P = 0.035). Although tadalafil’s prolonged effect on improving sexual function is an important factor, no…
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