Evidence Hub

The effect of self-care, self-efficacy, and health literacy on health-related quality of life in patients with hypertension: a cross-sectional study

Nastaran Salmanpour, Alireza Salehi, S. Nemati, M. Rahmanian, Alireza Zakeri, H. Drissi, Mohammad Reza Shadzi

BMC Public Health, 2025

427 participants · 20 citations

Abstract

Hypertension is a common chronic disease that negatively affects health-related quality of life (HRQOL). Identifying modifiable factors influencing HRQOL is essential to improve patient outcomes. This study focuses on self-care, self-efficacy, and health literacy due to their established role in chronic disease management and their potential to be enhanced through targeted interventions. These variables were selected based on Social Cognitive Theory and the Health Literacy Skills Framework, which highlight the roles of self-efficacy and health literacy in promoting effective self-care and improving health outcomes. In this cross-sectional study, data on HRQOL, self-care, self-efficacy, and health literacy were collected from 427 patients selected through systematic random sampling between March 2023 and March 2024 in community and private sector clinics affiliated with Shiraz University of Medical Sciences, Shiraz, Iran. Data were obtained via interviews using validated questionnaires, including WHOQOL-BREF, Hill-Bone, HBP-SCP, and HELIA-SF, along with patients’ demographic, anthropometric, and physiological information. A multiple linear regression model was used for data analysis. Additionally, logistic regression was performed to estimate odds ratios (ORs) for categorized HRQOL outcomes. The mean (SD) age of participants was 60.1 (11.1) years, with the majority (68.4%) being women. The mean (SD) scores for total HRQOL, self-care, self-efficacy, and health literacy were…

How strong is the evidence?

Evidence Hub reads this as a cross-sectional, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause. Reported size: 427 participants or records.

How the five levels of evidence work. The level is assigned automatically from the abstract and can be wrong, so check the paper.

Read the paper

Related studies

Go deeper in Evidence Hub

Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.

Open this study Sign up free