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Impact of symptom burden clusters on self-efficacy and quality of life in hemodialysis patients: a multicenter cross-sectional study

Alaa S Attoun, Dania Abuhalima, Samah W. Al-Jabi, S. Zyoud

Scientific Reports, 2025

306 participants · 13 citations

Abstract

Hemodialysis is a therapeutic procedure used to manage and treat acute and chronic kidney failure, which cannot respond to traditional medical therapy. Patients undergoing hemodialysis frequently experience multiple burdensome symptoms that impact their psychological and physical well-being. Understanding how symptom burden influences self-efficacy and quality of life is essential to improve care for this population. This study aimed to evaluate the impact of physical and mental health symptoms on self-efficacy in managing the chronic disease and quality of life among patients undergoing haemodialysis. This was a multicentre cross-sectional study, including two large hemodialysis centers at An-Najah National University Hospital, Nablus, and Al-Hussein Government Hospital in Beit Jala. The symptom clusters experienced by patients undergoing hemodialysis were assessed via the Dialysis Symptom Index. Self-efficacy and quality of life were assessed using the Self-Efficacy for Managing Chronic Disease 6-Item Scale (SEMCD-6) and the EuroQol-5 Dimension (EQ-5D-5L), respectively. Independent-samples t-test and one-way ANOVA assessed group differences in self-efficacy and quality of life, and multivariable linear regression identified independent predictors of these outcomes. This study involved 306 patients undergoing hemodialysis, with a mean age of 58.1 ± 13.3 years. More than half of the participants were female (54.9%), and most lived in cities (51.0%). More than two-thirds of…

How strong is the evidence?

Evidence Hub reads this as a cross-sectional, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause. Reported size: 306 participants or records.

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