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Gut microbiome characteristics in subjective cognitive decline, mild cognitive impairment and Alzheimer's disease: a systematic review and meta‐analysis

Guan-Lin Chen, Xiaoqi Zhou, Yi-Kang Zhu, Wen-Dian Shi, Kong Li

European Journal of Neurology, 2023

43 citations

Abstract

The gut microbiome has been reported to be closely related to Alzheimer's disease (AD) progression. Here, a comprehensive meta‐analysis of gut microbial characteristics in AD, mild cognitive impairment (MCI) and subjective cognitive decline (SCD) was performed to compare gut microbial alterations at each stage.

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Evidence Hub reads this as a systematic review. Its evidence level is 1 of 5 (Highest · pooled evidence). Pooled evidence from several studies sits at the top of the evidence pyramid.

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