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Improving immune‐related health outcomes post‐cesarean birth with a gut microbiome‐based program: A randomized controlled trial

Pamela A Nieto, Claudia Nakama, Julian M. Trachsel, David Goad, Taylor K Soderborg, Danielle S Tan, A. Orlandi, Qian Yuan et al.

Pediatric Allergy and Immunology, 2025

4 citations

Abstract

Infants born via Cesarean section (C‐section) often have a distinct gut microbiome and higher risks of atopic and immune‐related conditions than vaginally delivered infants. We evaluated whether a microbiome‐based program could shift gut microbiome composition and improve microbiome‐associated health outcomes in C‐section born infants.

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Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design.

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