Yoga and the Gut-Brain Axis: A Systematic Review of its Impact on Mental Health and the Gut Microbiome
Abstract
Background: The gut-brain axis (GBA) represents a complex, bidirectional communication network that connects the emotional and cognitive centers of the central nervous system with peripheral intestinal functions. This intricate system, which includes the enteric nervous system, the vagus nerve, and the hypothalamic-pituitary-adrenal axis, is profoundly influenced by the gut microbiome. Dysregulation of the GBA and a resulting microbial imbalance, or dysbiosis, have been implicated in the pathophysiology of both gastrointestinal disorders and mental health conditions, such as anxiety and depression. Yoga, an ancient mind-body practice, is increasingly being explored as a non-pharmacological therapeutic intervention for stress-related illnesses.
Objectives: The objective of this report is to conduct a narrative synthesis of the available evidence to explore the impact of yoga on mental health and the gut microbiome, with a particular focus on the mediating role of the GBA. A secondary objective is to contextualize these modern scientific findings within the framework of classical Ayurvedic principles, which have long posited a fundamental connection between the mind and digestive health.
Methods: This review is a structured narrative synthesis based on a curated set of research materials, not a de novo systematic review. The methodology for reporting aligns with the Preferred Reporting Items for Systematic reviews and Meta-Analyses statement to ensure transparency and…
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Evidence Hub reads this as a systematic review. Its evidence level is 1 of 5 (Highest · pooled evidence). Pooled evidence from several studies sits at the top of the evidence pyramid.
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