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Re: Prevalence of Nephrolithiasis in Patients with Chronic Liver Disease: A Case-Control Study

D. Assimos

Journal of Urology, 2019

Abstract

available at http://www.ncbi.nlm.nih.gov/pubmed/30563998 Editorial Comment: This small case controlled study reveals that prevalence of nephrolithiasis history is considerably increased in those afflicted with chronic liver disease. Oxidative stress and inflammation are more common in this cohort, both of which are thought to influence kidney stone formation. In this series body mass index was higher in those with liver disease. The association between obesity and kidney stone formation is well established. Some of these patients had nonalcoholic steatohepatitis. Further and more broad based studies are needed to confirm the association between liver disease and kidney stone formation. Dean G. Assimos, MD Suggested Reading Zhou T, Watts K, Agalliu I et al: Effects of visceral fat area and other metabolic parameters on stone composition in patients undergoing percutaneous nephrolithotomy. J Urol 2013; 190: 1416. Patel ND, Ward RD, Calle J et al: Computerized tomography based diagnosis of visceral obesity and hepatic steatosis is associated with low urine pH. J Urol 2017; 198: 1085. Ma S, Zhu XY, Eirin A et al: Perirenal fat promotes renal arterial endothelial dysfunction in obese swine through tumor necrosis factor-a. J Urol 2016; 195: 1152. Re: Dietary Oxalate and Kidney Stone Formation T. Mitchell, P. Kumar, T. Reddy, K. D. Wood, J. Knight, D. G. Assimos and R. P. Holmes Department of Urology, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama Am J…

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