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Cavitation DUE to COVID-19: a case of secondary atypical mycobacterial infection post-COVID-19

Milind Bhagat, B. Bevill

Chest, 2021

Abstract

TOPIC: Chest Infections TYPE: Fellow Case Reports INTRODUCTION: The novel Coronavirus disease 2019 pandemic has caused over 2 million deaths worldwide. Two recent systematic reviews and 1 meta-analysis reviewing the CT chest findings of COVID-19 did not reveal cavitation as a common finding with a recent retrospective review estimating the prevalence to be around 3.3%. Among the published examples, about half are solitary cavitary lesions. Most common causative organisms include staphylococcus aureus, klebsiella, and Enterobacter cloacae complex. A recently published case series described 6 cases of co-infection of Mycobacterium tuberculosis with COVID-19 causing cavitary lung disease. We report a case of Mycobacterium Avium Complex (MAC) infection causing cavitary lung disease as a complication of COVID-19 pneumonia. CASE PRESENTATION: 39 year old female with type 2 diabetes and hypothyroidism with a recent diagnosis of COVID-19 and pulmonary embolism. She presented with worsening cough, hemoptysis and left sided chest pain.CT Chest on admission showed a 7cm left lower lobe abscess with an associated pleural effusion and a left lower lobe pulmonary embolism along with scattered ground glass and consolidative opacities. Initial hospital treatment included prednisone, levofloxacin, and apixaban. One week after discharge she was readmitted with worsening left sided chest pain with scant hemoptysis.On readmission, workup included mycobacterial, fungal, auto-immune and HIV tests…

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