Outcomes and Prognostic Factors in 267 Patients with Severe Acute Respiratory Syndrome in Hong Kong
Abstract
Context Few large studies have described the presentation and course of patients with laboratory-confirmed severe acute respiratory syndrome (SARS). Contribution This retrospective study from a Hong Kong hospital found that most of the 227 patients with laboratory-confirmed SARS presented with fever (99%), chills (75%), myalgia (50%), pulmonary infiltrates (95%), and lymphopenia (70%). Some had cough (40%), shortness of breath (20%), and rales (20%). During hospitalization, half had diarrhea and one fourth required intensive care for respiratory failure. The 3-month mortality rate was 12%. Implications Some patients with SARS do not present with respiratory symptoms even though they have lung infiltrates. The Editors The epidemic of severe acute respiratory syndrome (SARS) struck Hong Kong in late February 2003. The number of cases surged quickly. As of this writing, 1755 probable or confirmed cases of SARS have occurred, resulting in 299 deaths (1). A novel coronavirus was identified as the causative agent (2, 3). Princess Margaret Hospital is a tertiary care hospital in Hong Kong that contains 1200 beds, 32 general wards, 3 isolation wards for admitting patients with communicable diseases, and 1 intensive care unit. It is 1 of the major centers providing infectious disease services in this locality. It began to admit patients who were suspected of having SARS on 26 February 2003. On 29 March 2003, the Hospital Authority of Hong Kong decided to convert Princess Margaret…
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