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A43-01 Unrecognized Desaturation Preceding Infectious Exacerbation in Idiopathic Pulmonary Fibrosis: Insight From Retrospective Bora Care® Monitoring

S. Balbolia, M. Le Garrec, A. Toullec, A. Deschodt, S. Le Liepvre, P. Chauvin, M. Kerjouan, M. Pirotais et al.

American Journal of Respiratory and Critical Care Medicine, 2026

Abstract

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive interstitial lung disease with unpredictable exacerbations that can rapidly become life-threatening. Patients often underestimate their symptoms because of gradual adaptation to chronic dyspnea, which complicates early recognition of exacerbations. Bora band® (Biosency, France) is a CE-marked wearable device that continuously records oxygen saturation (SpO2), respiratory rate (RR), heart rate (HR) and physical activity, and allows automatic data transmission to Bora connect® a secured remote monitoring platform. In this case, the data were reviewed retrospectively, after the patient’s clinical decline.

A 55-year-old man, former smoker, had biopsy-proven IPF diagnosed three years earlier with chronic hypoxemic respiratory failure treated with ambulatory oxygen and pulmonary rehabilitation. His medical history included well-controlled hypertension. In May 2025, Horton disease was diagnosed and treated with corticosteroids. On 23 June 2025, he reported increased dyspnea and fatigue.Despite his pulmonologist’s advice on 30 June, he initially refused hospitalization. Angio-CT-scan excluded pulmonary embolism but revealed new bilateral ground-glass opacites. Levofloxacin and cotrimoxazole were initiated.Continuous Bora band® data revealed a progressive decline in SpO2 (nadir of 86% despite oxygen supplementation), increased in RR, stable HR and a reduced activity, consistent with physiologic deterioration which was…

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