Post-COVID-19-associated aspergillus empyema and parenchymal abscess
Abstract
TOPIC: Chest Infections TYPE: Medical Student/Resident Case Reports INTRODUCTION: Coronavirus disease 19 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is associated with an increased risk of superimposed bacterial and fungal infections. Invasive aspergillosis has been found in critically ill COVID patients. Despite this strong association, there are no reports of aspergillus empyema related to COVID-19 pneumonia. Here, we present a case of post COVID-19 pneumonia complicated by aspergillus empyema and abscess. CASE PRESENTATION: A 38-year-old woman with a history of poorly controlled type II diabetes mellitus, and uncomplicated asymptomatic COVID-19 pneumonia 2 months prior, presented with 1 month of worsening productive cough, pleuritic chest pain, dyspnea, and fatigue. On admission, she was afebrile, tachycardiac, tachypneic with decreased right sided breath sounds and rhonchi. Her initial labs revealed a white blood cell count of 11.18 k/mcL, a chest x-ray revealed a right posterior lung field cavity with air-fluid level with right upper and lower lung field opacification (Fig. 1). Chest CT showed a right 16 x 5.5-centimeter rim enhancing consolidative opacity with air-fluid level and effusion (Fig. 3). Ultrasound guided thoracentesis revealed frank pus with pleural fluid studies pertinent for glucose 281 mg/dl, total protein 3.7 mg/dl, and fungal culture positive for Aspergillus niger. She underwent right-sided 14-french pigtail…
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Evidence Hub reads this as a case series, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health. Reported size: 19 participants or records.
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