Severe Mucus Plugging Causing Acute Hypoxic Respiratory Failure and Delayed Hemoptysis in a Renal Transplant Recipient Without Chronic Pulmonary Disease
Abstract
Mucus plugging is typically associated with chronic pulmonary diseases such as asthma, chronic obstructive pulmonary disease, and allergic bronchopulmonary aspergillosis. Clinically significant mucus plugging leading to acute respiratory failure in patients without underlying lung disease is rare. We present the case of a 36-year-old female patient with a history of renal transplantation who developed acute hypoxic respiratory failure requiring intubation due to extensive mucus plugging, followed by recurrent hemoptysis after extubation. Repeat bronchoscopy revealed significant tracheal granulation tissue and infection with methicillin-sensitive Staphylococcus aureus. This case highlights the potential for severe airway obstruction and delayed postintubation complications in patients without known chronic pulmonary conditions, particularly in the setting of recent intubation and immunosuppression.
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