Congenital Asplenia Revealed by Streptococcus oralis septicemia: Case Report
Abstract
Congenital asplenia is a rare life-threatening condition, often presenting with sepsis caused by encapsulated
pathogens. It may arise as part of situs abnormalities or result from an unrelated specific defect of spleen
development. Isolated congenital asplenia is a very rare condition. We report a case of asplenia revealed by severe
sepsis and multi-organ failure in a previously healthy 25-year-old male how had never undergone any surgical
procedures. Blood cultures grew Streptococcus oralis four days after admission. Computed tomography revealed
pneumonia and asplenia. The patient was finally diagnosed as Streptococcal sepsis revealing isolated congenital
asplenia. Cephalosporin and levofloxacin were administered and the patient died following cardiopulmonary arrests.
No family history for this condition was reported. Clinicians should pay attention to the congenital asplenia in
Streptococcal disease, particularly in the event of overwhelming sepsis. In affected individuals, the use of
appropriate antibiotic prophylaxis and immunisations could save lives.
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