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Monocyte Activation: The Link between Obstructive Sleep Apnea and Cardiovascular Disease?

P. Borker, Sanjay R. Patel

American Journal of Respiratory and Critical Care Medicine, 2022

7 citations

Abstract

1. Gattarello S, Borgatta B, Sol e-Viol an J, Vall es J, Vidaur L, Zaragoza R, et al.; Community-Acquired Pneumonia en la Unidad de Cuidados Intensivos II Study Investigators*. Decrease in mortality in severe community-acquired pneumococcal pneumonia: impact of improving antibiotic strategies (2000-2013). Chest 2014;146:22–31. 2. Ruhnke GW, Coca-Perraillon M, Kitch BT, Cutler DM. Marked reduction in 30-day mortality among elderly patients with community-acquired pneumonia. Am J Med 2011;124:171–178.e1. 3. Waterer GW, Self WH, Courtney DM, Grijalva CG, Balk RA, Girard TD, et al. In-hospital deaths among adults with community-acquired pneumonia. Chest 2018;154:628–635. 4. Simpson JC, Macfarlane JT, Watson J, Woodhead MA; British Thoracic Society Research Committee and Public Health Laboratory Service. A national confidential enquiry into community acquired pneumonia deaths in young adults in England and Wales. Thorax 2000;55:1040–1045. 5. Dean NC, Vines CG, Carr JR, Rubin JG, Webb BJ, Jacobs JR, et al. A pragmatic, stepped-wedge, cluster-controlled clinical trial of real-time pneumonia clinical decision support. Am J Respir Crit Care Med 2022; 205:1330–1336. 6. Dean NC, Jones BE, Jones JP, Ferraro JP, Post HB, Aronsky D, et al. Impact of an electronic clinical decision support tool for emergency department patients with pneumonia. Ann Emerg Med 2015;66:511– 520. 7. Jones BE, Ying J, Stevens V, Haroldsen C, He T, Nevers M, et al. Empirical anti-MRSA vs standard antibiotic…

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Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design.

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