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Aspiration Pneumonia Among Stroke Patients in Ethiopia: Systematic Review and Meta-Analysis

A. Getie, Manay Ayalneh, M. Bimerew, A. Wondmieneh

Clinical Epidemiology and Global Health, 2024

5 citations

Abstract

IntroductionOne of the main complications for stroke patients is aspiration pneumonia, which is an acute lung infection brought on by the entry of endogenous flora and various bodily substances from the gastrointestinal tract into the respiratory system. Aspiration pneumonia following a stroke was linked to older age, gender, dysarthria, denture use, cerebral atrophy, and basal ganglia-infarcted foci. Despite improvements in care, the epidemiological and prognostic effects of pneumonia associated with stroke are increasing mortality and morbidity.ObjectiveTo assess the pooled prevalence of aspiration pneumonia among stroke patients in Ethiopia.MethodsSeveral databases, including PubMed/MEDLINE, EMBASE, Scopus, Google Scholar, African Journals Online (AJOL), grey literature, and articles from the repository of Ethiopian universities, were examined to find available articles. The data were extracted and sorted in Microsoft Excel and exported to STATA/MP 17.0 for analysis. The Newcastle-Ottawa (NOS) was employed to assess each study's qualities. A weighted inverse variance random-effects model with a 95 % confidence interval was used to examine the pooled prevalence of aspiration pneumonia. The Galbraith plot and funnel plot were used to evaluate heterogeneity and publication bias, respectively. To identify the possible cause of heterogeneity, subgroup analysis and meta-regression were performed. P-values less than 0.05 were considered statistically significant.ResultThe pooled…

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