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Comparison of fat‐free mass adjusted for overhydration obtained by bioelectrical impedance and computed tomography in critically ill patients with COVID‐19: A secondary analysis of a prospective cohort

A. García-Grimaldo, N. Rodríguez-Moguel, C. Hernández-Cárdenas, I. Osuna-Padilla

Nutrition in clinical practice, 2025

Abstract

Muscle mass is a strong predictor of clinical outcomes. However, its continuous monitoring is not always feasible in critically ill patients. Surrogate methods, such as bioelectrical impedance analysis (BIA), may be affected by overhydration (OH). The aim of this study was to evaluate the agreement of BIA‐derived fat‐free mass (FFM) adjusted for hydration status in comparison with muscle mass assessed by computed tomography (CT) in critically ill patients with pneumonia due to COVID 19.

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Evidence Hub reads this as a secondary / pooled analysis, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence.

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